Rapor Tarihi: 11.04.2026 19:37
| Course Title | Code | Language | Type | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|---|---|
| Cancer Biology | BIO628 | Turkish | Compulsory | 3 + 0 | 3.0 | 8.0 |
| Prerequisite Courses | |
| Course Level | Graduate |
| Mode of delivery | Face To Face |
| Course Coordinator | Dr. Öğr. Üyesi KUBİLAY İNCİ |
| Instructor(s) | Dr. Öğr. Üyesi KUBİLAY İNCİ (Güz) |
| Goals | Bu dersin amacı, kanserin genetiği, fizyolojisi ve güncel tedavi yöntemleri hakkında bilgi vermektir. |
| Course Content | 1. Learns the properties of normal and cancerous cells. 2. Learns the mechanism of conversion from normal cells to cancerous cells. 3. Learn the importance of genetic factors in cancer formation. 4. Learns the importance of external factors in cancer formation. 5. Learn the current treatment methods of cancer. |
| # | Öğrenme Kazanımı |
| 1 | It explains the fundamental characteristics of cancer (signal transduction, evasion of apoptosis, angiogenesis, etc.) at the molecular level and analyses the dynamic interactions between these characteristics. |
| 2 | It evaluates the roles of mutations in critical pathways such as Ras/MAPK, PI3K/Akt/mTOR, Wnt/β-catenin and Notch in cellular transformation. |
| 3 | Epithelial-Mesenchymal Transition (EMT) explains the mechanisms underlying circulating tumour cells (CTCs) and organotropism in terms of principles of cell biology. |
| 4 | Designs research by comparing the advantages and disadvantages of in vitro (3D cultures, organoids) and in vivo (PDX models, transgenic mice) models used in cancer research. |
| 5 | Understands the biological rationale behind new-generation biotechnological approaches such as monoclonal antibodies, small-molecule inhibitors and CAR-T cell therapy. |
| Week | Topics/Applications | Method |
|---|---|---|
| 1. Week | Introduction to Cancer Biology | Research, Presentation (Preparation) |
| 2. Week | Physical and Chemical Properties of Normal and Cancer Cells | Preparation, After Class Study, Research, Other Activities, Interview |
| 3. Week | Cell Cycle and Cancer | Presentation (Preparation) |
| 4. Week | DNA Damage and Repair | Presentation (Preparation) |
| 5. Week | Cancer and Genetics | Preparation, After Class Study, Research, Other Activities |
| 6. Week | Signal Pathways Playing a Role in Cancer | Presentation (Preparation) |
| 7. Week | Oncogenes, and Tumor Suppressor Genes | Presentation (Preparation), Practice |
| 8. Week | Mechanisms of oncogene formation | Preparation, After Class Study, Research, Presentation (Preparation), Practice |
| 9. Week | Tumor Viruses | Research, Other Activities, Practice |
| 10. Week | Current treatment approaches, the application of immunotherapy and gene therapy methods, and their investigation using epidemiological data | Preparation, After Class Study, Research, Other Activities, Interview, Presentation (Preparation), Fieldwork, Practice |
| 11. Week | Biology of Angiogenesis | Research |
| 12. Week | P53 and Apoptosis | Preparation, After Class Study, Research, Other Activities |
| 13. Week | Metastasis | Presentation (Preparation), Practice |
| 14. Week | Current Approaches in Cancer Treatment | Presentation (Preparation), Fieldwork, Practice |
| No | Program Requirements | Level of Contribution | |||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Improve the scientific knowledge in the field of Biology to a more advanced level. Use the advenced knowledge to innovate, interpret the results, to apply the results and to design unique projects | ✔ | |||||
| 2 | Gain the ability to identify scientific questions, compare, analyze and solve the problems independently. | ✔ | |||||
| 3 | Gain the skills of using the modern laboratory techniques and analysis methods in the field of biology. | ✔ | |||||
| 4 | Gain the ability to get the information by doing research, to evaluate, interpret and apply it. | ✔ | |||||
| 5 | Gain the ability of discussion, synthesis and applying the scientific knowledge. | ✔ | |||||
| 6 | Gain the ability to design experimental studies, do the applications and analyse the complicated results using advanced skills, like critical thinking, problem solving and deciding. | ✔ | |||||
| 7 | Use the scientific knowledge and apply the ability of problem solving, evaluate and analyse advanced concepts in interdiciplinary fields. | ✔ | |||||
| 8 | Gain the scientific knowledge to set up communication with the collegues. Gain the ability to follow and use of the literature. Gain the ability to share or present the results of his/her own studies with the scientists during a scientific conference, workshop or seminar. | ✔ | |||||
| 9 | Participate scientific collaborations effectively and lead a scientific study if necessary. | ✔ | |||||
| 10 | Follow the innovations in the field of biology. Gain the ability to find resources and to use the databases. | ✔ | |||||
| 11 | Find new or strategical approaches to solve an unpredicted or advanced problems. | ✔ | |||||
| 12 | Improve scientific knowledge where there is a little or limited data present. Gain the ability to connect the information from different scientific diciplines. | ✔ | |||||
| 13 | Find unique ideas and get in contact with the professionals in scientific topics using his/her knowledge and skills. | ✔ | |||||
| 13 | Find unique ideas and get in contact with the professionals in scientific topics using his/her knowledge and skills. | ✔ | |||||
| 15 | Follow novel developments in computational software and hardware systems related with biology, use this knowledge and skill in research. | ✔ | |||||
| 16 | Obey the ethical regulations and watch the ethical issues while designing a scientific study, collecting data, evaluating and publishing them. | ✔ | |||||
| 17 | Adopt life-long learning strategies during performing scientific studies. | ✔ | |||||
| Program Requirements | DK1 | DK2 | DK3 | DK4 | DK5 |
|---|---|---|---|---|---|
| PY1 | 4 | 4 | 4 | 4 | 4 |
| PY2 | 5 | 5 | 5 | 5 | 5 |
| PY3 | 4 | 4 | 4 | 4 | 4 |
| PY4 | 5 | 5 | 5 | 5 | 5 |
| PY5 | 4 | 4 | 4 | 4 | 4 |
| PY6 | 5 | 5 | 5 | 5 | 5 |
| PY7 | 3 | 3 | 3 | 3 | 3 |
| PY8 | 4 | 4 | 4 | 4 | 4 |
| PY9 | 3 | 3 | 3 | 3 | 3 |
| PY10 | 5 | 5 | 5 | 5 | 5 |
| PY11 | 5 | 5 | 5 | 5 | 5 |
| PY12 | 4 | 4 | 4 | 4 | 4 |
| PY13 | 5 | 5 | 5 | 5 | 5 |
| PY15 | 3 | 3 | 3 | 3 | 3 |
| PY16 | 4 | 4 | 4 | 4 | 4 |
| PY17 | 5 | 5 | 5 | 5 | 5 |
| Ders Kitabı veya Notu | Ders Kitabı veya Ders Notu bulunmamaktadır. |
|---|---|
| Diğer Kaynaklar |
|
| ECTS credits and course workload | Quantity | Duration (Hour) | Total Workload (Hour) | |
|---|---|---|---|---|
|
Ders İçi |
Class Hours | 14 | 3 | 42 |
|
Ders Dışı |
Preparation, After Class Study | 14 | 3 | 42 |
| Research | 14 | 3 | 42 | |
| Interview | 14 | 1 | 14 | |
| Presentation (Preparation) | 14 | 1 | 14 | |
|
Sınavlar |
Midterm | 1 | 2 | 2 |
| Homework | 1 | 4 | 4 | |
| Final | 1 | 2 | 2 | |
| Classroom Activities | 14 | 3 | 42 | |
| Total Workload | 204 | |||
| *AKTS = (Total Workload) / 25,5 | ECTS Credit of the Course | 8.0 | ||
