Rapor Tarihi: 11.04.2026 19:20
| Course Title | Code | Language | Type | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|---|---|
| Chromosome Structure and Mutations | BIO536 | Turkish | Compulsory | 3 + 0 | 3.0 | 8.0 |
| Prerequisite Courses | |
| Course Level | Graduate |
| Mode of delivery | Face to face |
| Course Coordinator | Prof. Dr. PINAR GÖÇ RASGELE |
| Instructor(s) | Prof. Dr. PINAR GÖÇ RASGELE (Güz) |
| Goals | Identification of organization of DNA molecule and folding structure to form a chromosome. Identification in changes in the structure of the DNA molecule and chromosome (mutations) and to identify the connection between mutation and evolution |
| Course Content | Identification of molecular organization, function, structure of DNA. Identification of mutation. Describe mutation types, the factors that cause mutations. Explaining the relationship between cancer and evolutionary change |
| # | Öğrenme Kazanımı |
| 1 | Observes the structure of chromosomes and the different types of chromosomes |
| 2 | Learns mutation definition, different mutation classifications, mutation types according to mutation classifications |
| 3 | Analyzes mutations in chromosome structure and number. Establishes a relationship between mutations and evolution and formation of new species |
| 4 | Learns classification of gene mutations, the occurrence and impact on living organisms |
| 5 | Understands the relationship between mutations and cancer |
| Week | Topics/Applications | Method |
|---|---|---|
| 1. Week | Molecular organization of the DNA molecule and chromosome morphology. | Presentation (Preparation) |
| 2. Week | Mutation and factors that cause mutations | Presentation (Preparation) |
| 3. Week | Mechanisms of action of physical mutagens | Research, Presentation (Preparation) |
| 4. Week | Mechanisms of action of chemical mutagens | Research, Presentation (Preparation) |
| 5. Week | Chromosome structural mutations | Research, Presentation (Preparation) |
| 6. Week | Mechanisms of chromosomal structural mutations | Research, Presentation (Preparation) |
| 7. Week | Chromosome number (genome) mutations | Research, Presentation (Preparation) |
| 8. Week | Mechanisms of chromosome number (genome) mutations | Research, Presentation (Preparation) |
| 9. Week | Autosomal chromosomes and autosomal chromosome diseases | Preparation, After Class Study, Research |
| 10. Week | Gonosomal chromosomes and gonosomal chromosome diseases | Preparation, After Class Study, Research |
| 11. Week | Mechanisms by which DNA damage is repaired by repair systems | Preparation, After Class Study, Research |
| 12. Week | The relationship between mutation and cancer involves mutations that occur in cancer genes. | Preparation, After Class Study, Research |
| 13. Week | Explaining cancer cytogenetics with examples | Preparation, After Class Study, Research |
| 14. Week | Explaining cancer cytogenetics with examples | Preparation, After Class Study, Research |
| No | Program Requirements | Level of Contribution | |||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Improve the scientific knowledge in the field of Biology to a more advanced level. Use the advenced knowledge to innovate, interpret the results, to apply the results and to design unique projects. | ✔ | |||||
| 2 | Gain the ability to identify scientific questions, compare, analyze and solve the problems independently. | ✔ | |||||
| 3 | Gain the skills of using the modern laboratory techniques and analysis methods in the field of biology. | ✔ | |||||
| 4 | Gain the ability to get the information by doing research, to evaluate, interpret and apply it. | ✔ | |||||
| 5 | Gain the ability of discussion, synthesis and applying the scientific knowledge. | ✔ | |||||
| 6 | Gain the ability to design experimental studies, do the applications and analyse the complicated results using advanced skills, like critical thinking, problem solving and deciding. | ✔ | |||||
| 7 | Use the scientific knowledge and apply the ability of problem solving, evaluate and analyse advanced concepts in interdiciplinary fields. | ✔ | |||||
| 8 | Gain the scientific knowledge to set up communication with the collegues. Gain the ability to follow and use of the literature. Gain the ability to share or present the results of his/her own studies with the scientists during a scientific conference, workshop or seminar. | ✔ | |||||
| 9 | Participate scientific collaborations effectively and lead a scientific study if necessary. | ✔ | |||||
| 10 | Follow the innovations in the field of biology. Gain the ability to find resources and to use the databases. | ✔ | |||||
| 11 | Find new or strategical approaches to solve an unpredicted or advanced problems. | ✔ | |||||
| 12 | Improve scientific knowledge where there is a little or limited data present. Gain the ability to connect the information from different scientific diciplines. | ✔ | |||||
| 13 | Find unique ideas and get in contact with the professionals in scientific topics using his/her knowledge and skills. | ✔ | |||||
| 14 | Have the ability to read, understand, speak and write a foreign language in order to contact with the scientists from all over the World. | ✔ | |||||
| 15 | Follow novel developments in computational software and hardware systems related with biology, use this knowledge and skill in research. | ✔ | |||||
| 16 | Obey the ethical regulations and watch the ethical issues while designing a scientific study, collecting data, evaluating and publishing them. | ✔ | |||||
| 17 | Adopt life-long learning strategies during performing scientific studies. | ✔ | |||||
| Program Requirements | DK1 | DK2 | DK3 | DK4 | DK5 |
|---|---|---|---|---|---|
| PY1 | 5 | 5 | 5 | 5 | 5 |
| PY2 | 5 | 5 | 5 | 5 | 5 |
| PY3 | 5 | 5 | 5 | 5 | 5 |
| PY4 | 5 | 5 | 5 | 5 | 5 |
| PY5 | 4 | 4 | 4 | 4 | 4 |
| PY6 | 3 | 3 | 3 | 3 | 3 |
| PY7 | 4 | 4 | 4 | 4 | 4 |
| PY8 | 5 | 5 | 5 | 5 | 5 |
| PY9 | 5 | 5 | 5 | 5 | 5 |
| PY10 | 5 | 5 | 5 | 5 | 5 |
| PY11 | 4 | 4 | 4 | 4 | 4 |
| PY12 | 4 | 4 | 4 | 4 | 4 |
| PY13 | 5 | 5 | 5 | 5 | 5 |
| PY14 | 5 | 5 | 5 | 5 | 5 |
| PY15 | 5 | 5 | 5 | 5 | 5 |
| PY16 | 4 | 4 | 4 | 4 | 4 |
| PY17 | 3 | 3 | 3 | 3 | 3 |
| Ders Kitabı veya Notu | Ders Kitabı veya Ders Notu bulunmamaktadır. |
|---|---|
| Diğer Kaynaklar |
|
| ECTS credits and course workload | Quantity | Duration (Hour) | Total Workload (Hour) | |
|---|---|---|---|---|
|
Ders İçi |
Class Hours | 14 | 3 | 42 |
|
Ders Dışı |
Preparation, After Class Study | 1 | 33 | 33 |
| Research | 1 | 45 | 45 | |
| Other Activities | 1 | 35 | 35 | |
|
Sınavlar |
Midterm | 1 | 2 | 2 |
| Homework | 1 | 45 | 45 | |
| Final | 1 | 2 | 2 | |
| Total Workload | 204 | |||
| *AKTS = (Total Workload) / 25,5 | ECTS Credit of the Course | 8.0 | ||
