Rapor Tarihi: 22.12.2025 19:25
| Course Title | Code | Language | Type | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|---|---|
| Surgical Methods in Experimental Animals | BIO522 | Turkish | Compulsory | 3 + 2 | 4.0 | 8.0 |
| Prerequisite Courses | |
| Course Level | Graduate |
| Mode of delivery | Face to Face |
| Course Coordinator | Doç. Dr. Salih Tunç KAYA |
| Instructor(s) | Doç. Dr. Salih Tunç KAYA (Güz) |
| Goals | The aim of this course is to provide students with practical general knowledge and skills about basic surgical techniques in experimental animals. |
| Course Content | Laboratory introduction and physical conditions required in the animal laboratory, animal cages, housing, and care, Experimental animal breeds, animal production, animal welfare, Preoperative and postoperative preparation, Use of surgical instruments, Anesthesia and euthanasia techniques, basic suture techniques, marking methods in experimental groups, Anatomy and histology of experimental animals, Experimental Animal Physiology, Ethical concepts in experimental animals and alternative methods to animal studies,Experimental studies planning, Animal diseases, quarantine, internal and external parasites, laboratory safety, Autopsy in experimental animals, Legal regulations in laboratory animals in our country and in the world, Experimental animal biochemistry, Ethics committees and filling out the ethics committee application form |
| # | Öğrenme Kazanımı |
| 1 | Learn the general characteristics of experimental animals. |
| 2 | Learn how to work with experimental animals and ethical rules |
| 3 | Knows drug delivery and injection techniques. |
| 4 | Practices basic surgical techniques in experimental animals |
| 5 | Learn how to create and apply experimental models. |
| Week | Topics/Applications | Method |
|---|---|---|
| 1. Week | Laboratory introduction and physical conditions required in the animal laboratory, animal cages, housing, and care (T) The functioning of the laboratory for experimental animals, types of animal cages, removing animals from the cage (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 2. Week | Experimental animal breeds, animal production, animal welfare (T) Laboratory animal handling techniques (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 3. Week | Preoperative and postoperative preparation, Use of surgical instruments (T) Laboratory animal handling techniques (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 4. Week | Anesthesia and euthanasia techniques, basic suture techniques, marking methods in experimental groups (T) Injection techniques (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 5. Week | Anatomy and histology of experimental animals (T) Anesthesia and suturing in the rat (P) | |
| 6. Week | Experimental Animal Physiology (T) Experimental Models for the Study of Diabetes (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 7. Week | Ethical concepts in experimental animals and alternative methods to animal studies (T) Rat blood collection techniques, heart blood collection technique and tracheostomy (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 8. Week | Experimental studies planning (T) In vivo tissue perfusion (P) / Mid Term | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 9. Week | Animal diseases, quarantine, internal and external parasites, laboratory safety (T) Measurement of blood pressure in rat in vivo (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 10. Week | Autopsy in experimental animals (T). Autopsy (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 11. Week | Legal regulations in laboratory animals in our country and in the world (T) Hypertension models (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 12. Week | Experimental animal biochemistry (T) Ovariectomy (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 13. Week | Ethics committees and filling out the ethics committee application form (T) Detection of the estrous period in the rat, testicular biopsy and sperm collection, in vivo sperm collection (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| 14. Week | Homework presentations (T) Recording of physiological data in rat: Myocardial ischemia and reperfusion injury, ECG recording (P) | Preparation, After Class Study, Research, Other Activities, Presentation (Preparation), Practice |
| No | Program Requirements | Level of Contribution | |||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |||
| 1 | Improve the scientific knowledge in the field of Biology to a more advanced level. Use the advenced knowledge to innovate, interpret the results, to apply the results and to design unique projects. | ✔ | |||||
| 2 | Gain the ability to identify scientific questions, compare, analyze and solve the problems independently. | ✔ | |||||
| 3 | Gain the skills of using the modern laboratory techniques and analysis methods in the field of biology. | ✔ | |||||
| 4 | Gain the ability to get the information by doing research, to evaluate, interpret and apply it. | ✔ | |||||
| 5 | Gain the ability of discussion, synthesis and applying the scientific knowledge. | ✔ | |||||
| 6 | Gain the ability to design experimental studies, do the applications and analyse the complicated results using advanced skills, like critical thinking, problem solving and deciding. | ✔ | |||||
| 8 | Gain the scientific knowledge to set up communication with the collegues. Gain the ability to follow and use of the literature. Gain the ability to share or present the results of his/her own studies with the scientists during a scientific conference, workshop or seminar. | ✔ | |||||
| 9 | Participate scientific collaborations effectively and lead a scientific study if necessary. | ✔ | |||||
| 10 | Follow the innovations in the field of biology. Gain the ability to find resources and to use the databases. | ✔ | |||||
| 11 | Find new or strategical approaches to solve an unpredicted or advanced problems. | ✔ | |||||
| 12 | Improve scientific knowledge where there is a little or limited data present. Gain the ability to connect the information from different scientific diciplines. | ✔ | |||||
| 13 | Find unique ideas and get in contact with the professionals in scientific topics using his/her knowledge and skills. | ✔ | |||||
| 14 | Have the ability to read, understand, speak and write a foreign language in order to contact with the scientists from all over the World. | ✔ | |||||
| 15 | Follow novel developments in computational software and hardware systems related with biology, use this knowledge and skill in research. | ✔ | |||||
| 16 | Obey the ethical regulations and watch the ethical issues while designing a scientific study, collecting data, evaluating and publishing them. | ✔ | |||||
| 17 | Adopt life-long learning strategies during performing scientific studies. | ✔ | |||||
| Program Requirements | DK1 | DK2 | DK3 | DK4 | DK5 |
|---|---|---|---|---|---|
| PY1 | 5 | 5 | 5 | 5 | 5 |
| PY2 | 5 | 5 | 5 | 5 | 5 |
| PY3 | 5 | 5 | 5 | 5 | 5 |
| PY4 | 5 | 5 | 5 | 5 | 5 |
| PY5 | 5 | 5 | 5 | 5 | 5 |
| PY6 | 5 | 5 | 5 | 5 | 5 |
| PY8 | 4 | 4 | 4 | 4 | 4 |
| PY9 | 5 | 5 | 5 | 5 | 5 |
| PY10 | 5 | 5 | 5 | 5 | 5 |
| PY11 | 5 | 5 | 5 | 5 | 5 |
| PY12 | 4 | 4 | 4 | 4 | 4 |
| PY13 | 5 | 5 | 5 | 5 | 5 |
| PY14 | 2 | 2 | 2 | 2 | 2 |
| PY15 | 2 | 2 | 2 | 2 | 2 |
| PY16 | 5 | 5 | 5 | 5 | 5 |
| PY17 | 4 | 4 | 4 | 4 | 4 |
| Ders Kitabı veya Notu | Ders Kitabı veya Ders Notu bulunmamaktadır. |
|---|---|
| Diğer Kaynaklar |
|
| ECTS credits and course workload | Quantity | Duration (Hour) | Total Workload (Hour) | |
|---|---|---|---|---|
|
Ders İçi |
Class Hours | 14 | 3 | 42 |
|
Ders Dışı |
Preparation, After Class Study | 14 | 1 | 14 |
| Research | 14 | 3 | 42 | |
| Interview | 4 | 1 | 4 | |
| Presentation (Preparation) | 14 | 1 | 14 | |
| Practice | 14 | 2 | 28 | |
| Other Activities | 14 | 2 | 28 | |
|
Sınavlar |
Midterm 1 | 1 | 2 | 2 |
| Final | 1 | 2 | 2 | |
| Practice | 14 | 1 | 14 | |
| Classroom Activities | 14 | 1 | 14 | |
| Total Workload | 204 | |||
| *AKTS = (Total Workload) / 25,5 | ECTS Credit of the Course | 8.0 | ||
