Course Information

Course Information
Course Title Code Language Type Semester L+U Hour Credits ECTS
Pharmaceutical Toxicology 2 ECZ408 Turkish Compulsory 8. Semester 3 + 0 3.0 3.0
Prerequisite Courses
Course Level Undergraduate
Mode of delivery Lecture, discussion, question and answer,
Course Coordinator Dr. Öğr. Üyesi Didem ORAL
Instructor(s)
Goals Poisonings, drug interactions, toxicity mechanisms in poisonings, drug interactions and poisonings in specific patient groups, knowledge about drug poisonings
Course Content Poisonings, Drug Interactions, Toxicity Mechanisms in Poisonings, Drug Interactions and Poisonings in Special Patient Groups, Drug Poisonings, Pesticide Toxicology, Heavy Metal Toxicity: Lead, Mercury, Arsenic, and Cadmium, Toxic Effects of Nonsteroidal Anti-Inflammatory Drugs, Toxic Effects of Antidepressant Drugs, Toxic Effects of Vitamins
Learning Outcomes
# Öğrenme Kazanımı
1 Identify medicinal, poisonous or narcotic plants
2 Evaluating the metabolism of the active pharmaceutical ingredient
3 Providing consultancy on the rational and safe use of dietary supplements
4 Informing patients and relevant healthcare personnel about rational and safe drug use in special patient groups
5 Detecting and evaluating drug-drug/food/natural medicinal product/disease interactions
6 Detecting and evaluating side/adverse effects of drugs and vaccines
7 Evaluating the toxic effects of drugs
8 Providing advice on public health matters
Lesson Plan (Weekly Topics)
Week Topics/Applications Method
1. Week Toxicity research, Toxicity tests Class Hours Interview Other Activities Presentation (Preparation)
2. Week Alcohol poisoning Other Activities Class Hours Preparation, After Class Study Interview Presentation (Preparation) Research
3. Week Household chemical poisoning Other Activities Presentation (Preparation) Preparation, After Class Study Class Hours Interview
4. Week Heavy Metal Toxicity: Lead, Mercury, Arsenic, and Cadmium Research Preparation, After Class Study Other Activities Presentation (Preparation) Class Hours Interview
5. Week Natural toxins Presentation (Preparation) Interview Other Activities Class Hours Research Preparation, After Class Study
6. Week Pesticide Toxicology Other Activities Interview Presentation (Preparation) Preparation, After Class Study Research Class Hours
7. Week Radioactivity Other Activities Interview Presentation (Preparation) Preparation, After Class Study Class Hours Research
8. Week Drug interactions 1 Research Class Hours Other Activities Preparation, After Class Study Presentation (Preparation) Interview
9. Week Drug interactions 2 Other Activities Research Preparation, After Class Study Presentation (Preparation) Interview Class Hours
10. Week Drug toxicity Interview Presentation (Preparation) Preparation, After Class Study Research Class Hours Other Activities
11. Week The Toxic Effects of Nonsteroidal Anti-Inflammatory Drugs Presentation (Preparation) Class Hours Preparation, After Class Study Interview Other Activities Research
12. Week Drug toxicity in special patient groups Research Other Activities Class Hours Interview Presentation (Preparation) Preparation, After Class Study
13. Week Antidepressants, Narcotics The Toxic Effects of Drugs Research Preparation, After Class Study Other Activities Presentation (Preparation) Interview Class Hours
14. Week The Toxic Effects of Vitamins Class Hours Research Preparation, After Class Study Other Activities Interview Presentation (Preparation)
*Midterm and final exam dates are not specified in the 14-week course operation plan. Midterm and final exam dates are held on the dates specified in the academic calendar with the decision of the University Senate.
The Matrix for Course & Program Learning Outcomes
No Program Requirements Level of Contribution
1 2 3 4 5
1 Uses the knowledge and skills acquired by completing the pharmacy undergraduate programme in the application areas of the profession by taking initiative when necessary within the framework of ethical and deontological rules in line with the current laws, regulations and legislation.
2 Has sufficient knowledge and application skills about the physical and chemical structure, synthesis, microbiological and toxicological analysis, effects, structure-effect relationships, design and development, therapeutic dose determination, pharmacokinetic and pharmacodynamic properties of active and excipients, pharmaceutical preparations and medicinal products.
3 By adopting lifelong learning, pharmacy professional practices, science, technology, contemporary thinking and behaviour in the dimension of current information in the dimension of technological tools, databases and information resources. Develops, deepens, evaluates and uses this information for the benefit of society.
4 Takes an active role in the preparation, production, quality assurance and control, bioavailability and bioequivalence, licensing and patent studies, supply chain management and presentation of pharmaceutical, radiopharmaceutical, biotechnological, nanotechnological and cosmetic/cosmeceutical products containing natural or synthetic active ingredients.
5 Takes an active role in pharmacovigilance practices; uses the adverse effect reporting system; contributes to risk management and audit to ensure safe drug use.
6 Informs the patient, patient relatives and other health professionals to increase awareness of drug safety.
7 He/she has sufficient knowledge about the preparation of major medicines, the use and legislation of all original or generic preparations and medicinal products.
8 Has knowledge about the indications, route of administration and incompatibilities of the drugs prescribed to the patient, evaluation of clinical laboratory results in order to ensure and promote the most appropriate use of drugs within the framework of rational drug use.
9 Food supplements, nutraceuticals, cosmetics / cosmeceuticals, OTC, etc. has the competence to provide practical and useful information to the public about products.
10 Integrates and develops pharmacy professional knowledge with knowledge from different disciplines within the framework of pharmaceutical care and clinical pharmacy practice.
11 To be able to communicate effectively with the relevant legal authorities, physicians and health personnel, pharmaceutical industry and other stakeholders in order to improve the health level and quality of life of the society, and to be able to bring suggestions and solutions to the problems related to the field.
12 Has knowledge about the properties, usage areas, production, quality assurance, legislation and legal regulations of medical devices used for chronic diseases and other purposes.
13 They take part in the supply and presentation of pharmaceuticals and medical products and provide counselling services to patients on rational and safe use.
14 To be able to follow the information and developments in pharmacy practice areas by using at least one foreign language, to communicate with patients and colleagues, to express himself/herself verbally and in writing by participating in national and / or international activities and projects.
15 Has sufficient knowledge and application skills about various technological tools, information resources, software and artificial intelligence supported technologies required by pharmacy professional practice areas.
16 As a health professional providing primary health care services, provides healthy living counselling by managing patient records; promotes healthy living and fulfils professional responsibilities to protect public health.
17 He/she pays attention to the occupational safety of the employees under his/her responsibility and plans and manages their vocational training for their development within the framework of a project and monitors and evaluates the process.
18 Takes part in the development processes of the pharmacy profession and application areas related to pharmaceutical and health management; conducts research and development activities in accordance with scientific and ethical principles; analyses, evaluates, interprets and applies data.
19 Participates in quality management processes by documenting professional activities and practices effectively and safely in accordance with quality management and processes.
20 Be a role model for his/her colleagues and an example to the society with his/her attitude, behaviour and professional identity.
21 Has knowledge about anatomy, immunology, physiology, physiopathology and biochemistry of biological systems. Knows and relates the basic concepts of cognitive states and behaviours, mental and physical diseases, symptoms and treatments that affect human health.
Relations with Education Attainment Program Course Competencies
Program Requirements DK1 DK2 DK3 DK4 DK5 DK6 DK7 DK8
PY1 4 4 4 4 4 4 4 4
PY2 5 5 5 5 5 5 5 5
PY3 2 2 2 2 2 2 2 2
PY4 3 3 3 3 3 3 3 3
PY5 5 5 5 5 5 5 5 5
PY6 5 5 5 5 5 5 5 5
PY7 1 1 1 1 1 1 1 1
PY8 5 5 5 5 5 5 5 5
PY9 5 5 5 5 5 5 5 5
PY10 4 4 4 4 4 4 4 4
PY11 4 4 4 4 4 4 4 4
PY12 1 1 1 1 1 1 1 1
PY13 5 5 5 5 5 5 5 5
PY14 1 1 1 1 1 1 1 1
PY15 1 1 1 1 1 1 1 1
PY16 4 4 4 4 4 4 4 4
PY17 5 5 5 5 5 5 5 5
PY18 2 2 2 2 2 2 2 2
PY19 1 1 1 1 1 1 1 1
PY20 1 1 1 1 1 1 1 1
PY21 3 3 3 3 3 3 3 3
Recommended Sources
Ders Kitabı veya Notu Ders Kitabı veya Ders Notu bulunmamaktadır.
Diğer Kaynaklar
  • Ders Kitabı veva Notu Erdem, O., & Bacanlı, M. (Ed.). (2021). Temel Toksikoloji (1. basım). Ankara: Ankara Nobel Tıp Kitabevleri. Klaassen, C.D., Watkins J.W., "Casarett & Doull’s Essential of Toxicology, The McGraw Hill Companies, 2010. .Ellenhorn, M.J., "Medical Toxicology", Williams & Wilkins, Maryland, 1997. .Hayes, A.W., "Principles and Methods of Toxicology", Taylor & Francis, Philadelphia, 2001 Toksikolojinin Temelleri ("Casarett & Doull’s çeviri) Nobel Kitapevi, 2017).
ECTS credits and course workload
ECTS credits and course workload Quantity Duration (Hour) Total Workload (Hour)
Sınavlar
Midterm 1 1 1.5 1.5
Homework 1 13 1 13
Homework 2 13 1 13
Quiz 1 10 1 10
Quiz 2 9 1 9
Final 1 2 2
Classroom Activities 14 2 28
Total Workload 76.5
*AKTS = (Total Workload) / 25,5 ECTS Credit of the Course 3.0