Education Information System

Course Information

Course Information

Course Title	Code	Language	Type	Semester	L+U Hour	Credits	ECTS
Bıopharmaceutıcs And Pharmacokınetıcs	ECZ404	Turkish	Compulsory	8. Semester	2 + 0	2.0	3.0

Prerequisite Courses
Course Level	Undergraduate
Mode of delivery	Face to face
Course Coordinator
Instructor(s)
Goals	It aims to analyze the concepts of bioavailability, bioequivalence and pharmacokinetics, determination methods, mathematical evaluations, formulation parameters affecting these concepts, and examination of blood-time data of drugs with mathematical models, compartment models and/or noncompartmental models.
Course Content	Terminology related to biopharmaceutical-pharmacokinetics, Pharmacokinetics, dosage form design relationship, Bioavailability and determination methods, its importance, Bioavailability enhancement recommendations, Importance of bioequivalence determination methods, Compartment models, Peeling Method

Learning Outcomes

#	Öğrenme Kazanımı
1	Learns terminological concepts related to biopharmaceutics and pharmacokinetics.
2	Learns the concepts of bioavailability and bioequivalence.
3	Gains information about linear and nonlinear pharmacokinetics and determination.
4	Gains information about the analysis of pharmacokinetic parameters from blood data by peeling method.

Lesson Plan (Weekly Topics)

Week	Topics/Applications	Method
1. Week	Terminology about Biopharmaceutics and Pharmacokinetics
2. Week	Relationship of pharmacokinetic and dosage form design
3. Week	Relationship of pharmacokinetic and dosage form design
4. Week	Bioavailability analyses methods and importance
5. Week	Bioavailability analyses methods and importance
6. Week	Bioavailability enhancement suggestions
7. Week	Bioavailability enhancement suggestions
8. Week	Midterm
9. Week	Bioequivalence analysis methods and importance
10. Week	Bioequivalence enhancement suggestions
11. Week	Compartmental models
12. Week	Compartmental models
13. Week	Compartmental models
14. Week	Stripping / Peeling method
15. Week	Stripping / Peeling method

*Midterm and final exam dates are not specified in the 14-week course operation plan. Midterm and final exam dates are held on the dates specified in the academic calendar with the decision of the University Senate.

Relations with Education Attainment Program Course Competencies

Program Requirements	DK1	DK2	DK3	DK4

Recommended Sources

Ders Kitabı veya Notu	Ders Kitabı veya Ders Notu bulunmamaktadır.
Diğer Kaynaklar	Modern Farmasötik Teknoloji, F. Acartürk, İ. Ağabeyoğlu, N. Çelebi, T. Değim, Z. Değim, T. Doğanay, S. Takka, F. Tırnaksız, Türk Eczacılar Birliği, Eczacılık Akademisi Yayını Yayın No: 1, Ankara, 2007. Farmasötik Teknoloji, Temel Konular ve Dozaj Şekilleri, Ed.: Ayla Z. Gürsoy, Kontrollü Salım Sistemleri Derneği Yayını No: 2, İstanbul, 2004. Bourne DWA, Pharmacokinetics, Ed: GS Banker, CT Rhodes, Modern Pharmacuetics, 4th ed., Marcel Dekker Inc., 2002 Gibaldi M, Perrier D. Pharmacokinetics, 2nd edition, Marcel Dekker Inc., 1982 Wagner JG, Fundamentals of Clinical Pharmacokinetics, Drug Intelligence Pub., 1979

ECTS credits and course workload

ECTS credits and course workload		Quantity	Duration (Hour)	Total Workload (Hour)
Sınavlar	Midterm 1	1	8	8
	Homework 1	1	5	5
	Final	1	10	10
	Classroom Activities	14	2	28
Total Workload				51
*AKTS = (Total Workload) / 25,5		ECTS Credit of the Course		25.5 3.0