| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Advanced Cell Physiology | BIO778 | 3 + 0 | 3.0 | 7.5 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assoc. Prof. Dr. Salih Tunç KAYA |
| Instructor(s) | |
| Assistants | |
| Goals | The aim of this course is to enable students to learn the physiological mechanisms that take place in the cell, the interactions of cells with each other and their environment. |
| Course Content | Homeostasis and cellular physiology, Diffusion and permeability, Osmotic pressure and water movement, Electrical Consequences of Ionic Gradients, Ion Channels, Passive Electrical Properties of Membranes, Generation and propagation of action potential, Ion Channel Diversity, Electrochemical Potential Energy and, Transport Processes, Passive Transport, Active Transport, Molecular Motors and Muscle Contraction Mechanism, Muscle Stimulation-Contraction Connection, Muscle Contraction Mechanism |
| Learning Outcomes |
- Learn the structure of the biological membrane and the transport of small and large molecules across the membrane - Learns signal transmission and regulation in the cell - Learn the details of nerve cells and signal transmission |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Introduction: Homeostasis and cellular physiology | Course Hours Preparation, After Class Study Verbal Expression Research Visual Presentation |
| 2. Week | Diffusion and permeability | Research Verbal Expression Visual Presentation Course Hours Preparation, After Class Study |
| 3. Week | Osmotic pressure and water movement | Course Hours Preparation, After Class Study Research Verbal Expression Visual Presentation |
| 4. Week | Electrical Consequences of Ionic Gradients | Visual Presentation Verbal Expression Course Hours |
| 5. Week | Ion Channels | Course Hours Preparation, After Class Study Research Verbal Expression Visual Presentation |
| 6. Week | Passive Electrical Properties of Membranes | Research Course Hours Verbal Expression Visual Presentation Preparation, After Class Study |
| 7. Week | Generation and propagation of action potential | Course Hours Verbal Expression Visual Presentation |
| 8. Week | Ion Channel Diversity / Mid Term | Course Hours Verbal Expression Visual Presentation |
| 9. Week | Electrochemical Potential Energy and Transport Processes | Verbal Expression Visual Presentation Course Hours |
| 10. Week | Passive Transport | Course Hours Visual Presentation Verbal Expression |
| 11. Week | Active Transport | Visual Presentation Course Hours Verbal Expression |
| 12. Week | Molecular Motors and Muscle Contraction Mechanism | Verbal Expression Visual Presentation Course Hours |
| 13. Week | Muscle Stimulation-Contraction Connection | Verbal Expression Visual Presentation Course Hours |
| 14. Week | Muscle Contraction Mechanism | Visual Presentation Verbal Expression Course Hours |
| Hücre Fizyolojisi, 2004, Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson, ISBN 0-323-01341-4, Elsevier |
| Hücre Fizyolojisi ve Nörofizyoloji, 2019, Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson, Elsevier Health Sciences |
| Cell Physiology, edited by Nicholas Sperelakis 2011 Elsevier Inc. ISBN:978-0-12-387738-3 https://doi.org/10.1016/C2010-0-66479-0 |
| Mechanisms in Cell Physiology, By Michele Mazzanti, Cambridge Scholars Publishing ISBN (10): 1-5275-8248-5 |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | Measurement Method |
|---|---|---|---|---|---|
| PY1 | 5 | 4 | 4 | 4 | 40,60 |
| PY2 | 3 | 3 | 3 | 3 | 40,60 |
| PY3 | 3 | 2 | 2 | 2 | - |
| PY4 | 4 | 4 | 4 | 4 | 40,60 |
| PY5 | 4 | 2 | 3 | 3 | 40,60 |
| PY6 | 5 | 5 | 5 | 5 | 40,60 |
| PY7 | 5 | 4 | 4 | 4 | 40,60 |
| PY10 | 5 | 5 | 5 | 5 | 40,60 |
| PY11 | 5 | 3 | 4 | 3 | 40,60 |
| PY12 | 5 | 4 | 3 | 4 | 40,60 |
| PY13 | 5 | 3 | 5 | 4 | 40,60 |
| PY14 | 4 | 4 | 4 | 4 | 40,60 |
| PY15 | 3 | 2 | 2 | 2 | 40,60 |
| PY16 | 3 | 3 | 3 | 2 | 40,60 |
| PY17 | 5 | 5 | 5 | 5 | 40,60 |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 14 | 1 | 14 |
| Research | 14 | 4 | 56 |
| Other Activities | 1 | 4 | 4 |
| Verbal Expression | 14 | 3 | 42 |
| Visual Presentation | 14 | 2 | 28 |
| Midterm 1 | 1 | 2 | 2 |
| Final | 1 | 2 | 2 |
| Classroom Activities | 1 | 1.25 | 1.25 |
| Total Workload | 191.25 | ||
| ECTS Credit of the Course | 7.5 | ||
