Course Title | Code | Semester | L+U Hour | Credits | ECTS |
---|---|---|---|---|---|
Surgical Methods in Experimental Animals | BIO777 | 3 + 2 | 4.0 | 7.5 |
Prerequisites | None |
Language of Instruction | Turkish |
Course Level | Graduate |
Course Type | |
Mode of delivery | Face to Face |
Course Coordinator |
Assoc. Prof. Dr. Salih Tunç KAYA |
Instructors | |
Assistants | |
Goals | The aim of this course is to provide students with practical general knowledge and skills about basic surgical techniques in experimental animals. |
Course Content | Laboratory introduction and physical conditions required in the animal laboratory, animal cages, housing, and care, Experimental animal breeds, animal production, animal welfare, Preoperative and postoperative preparation, Use of surgical instruments, Anesthesia and euthanasia techniques, basic suture techniques, marking methods in experimental groups, Anatomy and histology of experimental animals, Experimental Animal Physiology, Ethical concepts in experimental animals and alternative methods to animal studies,Experimental studies planning, Animal diseases, quarantine, internal and external parasites, laboratory safety, Autopsy in experimental animals, Legal regulations in laboratory animals in our country and in the world, Experimental animal biochemistry, Ethics committees and filling out the ethics committee application form |
Learning Outcomes |
- Learn the general characteristics of experimental animals. - Learn how to work with experimental animals and ethical rules - Knows drug delivery and injection techniques. - Practices basic surgical techniques in experimental animals - Learn how to create and apply experimental models. |
Week | Topics | Learning Methods |
---|---|---|
1. Week | Laboratory introduction and physical conditions required in the animal laboratory, animal cages, housing, and care (T) The functioning of the laboratory for experimental animals, types of animal cages, removing animals from the cage (P) | Preparation, After Class Study Practice Verbal Expression Research Course Hours Other Activities Visual Presentation |
2. Week | Experimental animal breeds, animal production, animal welfare (T) Laboratory animal handling techniques (P) | Practice Visual Presentation Preparation, After Class Study Verbal Expression Research Course Hours |
3. Week | Preoperative and postoperative preparation, Use of surgical instruments (T) Laboratory animal handling techniques (P) | Research Preparation, After Class Study Course Hours Verbal Expression Visual Presentation Practice |
4. Week | Anesthesia and euthanasia techniques, basic suture techniques, marking methods in experimental groups (T) Injection techniques (P) | Research Visual Presentation Course Hours Practice Verbal Expression Preparation, After Class Study |
5. Week | Anatomy and histology of experimental animals (T) Anesthesia and suturing in the rat (P) | Course Hours Research Preparation, After Class Study Verbal Expression Visual Presentation Practice |
6. Week | Experimental Animal Physiology (T) Experimental Models for the Study of Diabetes (P) | |
7. Week | Ethical concepts in experimental animals and alternative methods to animal studies (T) Rat blood collection techniques, heart blood collection technique and tracheostomy (P) | Preparation, After Class Study Research Practice Visual Presentation Course Hours Verbal Expression |
8. Week | Experimental studies planning (T) In vivo tissue perfusion (P) / Mid Term | Research Preparation, After Class Study Verbal Expression Visual Presentation Course Hours Practice |
9. Week | Animal diseases, quarantine, internal and external parasites, laboratory safety (T) Measurement of blood pressure in rat in vivo (P) | Course Hours Visual Presentation Research Practice Preparation, After Class Study Verbal Expression |
10. Week | Autopsy in experimental animals (T). Autopsy (P) | Course Hours Preparation, After Class Study Verbal Expression Visual Presentation Practice Research |
11. Week | Legal regulations in laboratory animals in our country and in the world (T) Hypertension models (P) | Course Hours Preparation, After Class Study Visual Presentation Research Practice Verbal Expression |
12. Week | Experimental animal biochemistry (T) Ovariectomy (P) | Course Hours Preparation, After Class Study Verbal Expression Visual Presentation Practice |
13. Week | Ethics committees and filling out the ethics committee application form (T) Detection of the estrous period in the rat, testicular biopsy and sperm collection, in vivo sperm collection (P) | Preparation, After Class Study Research Visual Presentation Practice Verbal Expression Course Hours |
14. Week | Homework presentations (T) Recording of physiological data in rat: Myocardial ischemia and reperfusion injury, ECG recording (P) | Course Hours Preparation, After Class Study Visual Presentation Verbal Expression Practice Research |
• Principles of Laboratory Animal Science, Revised Edition Edited by L.F.M. van Zutphen, V. Baumans, A.C. Beynen,2001, ELSEVIER, Amsterdam, The Netherlands, ISBN: 0-444-50612-8 |
• Introduction to Laboratory Animal Science and Technology, J.K. Inglis, Pergamon Press, GB, 1980 |
• The Design of Animal Experiments, Royal Society of Medicine Pr Ltd; 1st edition (January 1, 2002), ISBN-10: 1853155136 |
Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | Measurement Method |
---|---|---|---|---|---|---|---|
PY1 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY2 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY3 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY4 | 5 | 0 | 0 | 0 | 0 | 0 | - |
PY5 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY6 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY7 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY8 | 4 | 4 | 4 | 4 | 4 | 4 | - |
PY9 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY10 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY11 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY12 | 3 | 3 | 3 | 3 | 3 | 3 | - |
PY13 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY14 | 2 | 2 | 2 | 2 | 2 | 2 | - |
PY15 | 2 | 2 | 2 | 2 | 2 | 2 | - |
PY16 | 5 | 5 | 5 | 5 | 5 | 5 | - |
PY17 | 4 | 4 | 4 | 4 | 4 | 4 | - |
0 | 1 | 2 | 3 | 4 | 5 | |
---|---|---|---|---|---|---|
Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
Event | Quantity | Duration (Hour) | Total Workload (Hour) |
---|---|---|---|
Course Hours | 14 | 3 | 42 |
Research | 14 | 2 | 28 |
Verbal Expression | 2 | 2.625 | 5.25 |
Visual Presentation | 14 | 3 | 42 |
Practice | 14 | 2 | 28 |
Midterm 1 | 1 | 2 | 2 |
Final | 1 | 2 | 2 |
Classroom Activities | 14 | 3 | 42 |
Total Workload | 191.25 | ||
ECTS Credit of the Course | 7.5 |