| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Cardiac Electrophysiology | BIO629 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to Face |
| Course Coordinator |
Assoc. Prof. Dr. Salih Tunç KAYA |
| Instructor(s) | |
| Assistants | |
| Goals | The aim of this course is to enable students to comprehend the electrical activity of the heart muscle at the cellular and molecular level and to define the rhythm disorders observed because of the disruption of electrical activity. |
| Course Content | Cardiomyocyte Electrical Function, Cardiac Impulse Initiation and Propagation, Structural and Molecular Bases of Cardiac Ion Channel Function, Models of Cardiac Excitation, Normal Electrocardiogram, Electrocardiographic Interpretation of Heart Muscle and Coronary Blood Flow Disorders: Calculations with Vectors, Cardiac Arrhythmias and Interpretations Based on Electrocardiography, Myocardial Ischemia and Reperfusion Injury, Arrhythmia Mechanisms, Supraventricular Tachyarrhythmias: Mechanisms, Features, and Management,Ventricular Tachyarrhythmias: Mechanisms, Features, and Management, Bradyarrhythmia, Neural Control of Cardiac Electrical Activity and Cardiac Arrhythmias, Sex and Age Differences in Arrhythmias |
| Learning Outcomes |
- Knows the Electrical Function of the Heart - Can interpret the contraction of the heart muscle based on electrocardiography - Knows Cardiac Arrhythmias and can interpret them based on Electrocardiography - May explain the cellular and molecular mechanisms of cardiac arrhythmias - It may explain the cellular mechanism of myocardial ischemia and reperfusion injury and the observed arrhythmias as a result of the damage |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Cardiomyocyte Electrical Function | Verbal Expression Visual Presentation Course Hours |
| 2. Week | Cardiac Impulse Initiation and Propagation | Verbal Expression Visual Presentation Course Hours |
| 3. Week | Structural and Molecular Bases of Cardiac Ion Channel Function | Course Hours Visual Presentation Verbal Expression |
| 4. Week | Models of Cardiac Excitation | |
| 5. Week | Normal Electrocardiogram | Visual Presentation Verbal Expression Course Hours |
| 6. Week | Electrocardiographic Interpretation of Heart Muscle and Coronary Blood Flow Disorders: Calculations with Vectors | Course Hours Visual Presentation Verbal Expression |
| 7. Week | Cardiac Arrhythmias and Interpretations Based on Electrocardiography | Course Hours Verbal Expression Visual Presentation |
| 8. Week | Myocardial Ischemia and Reperfusion Injury / Mid Term | Verbal Expression Visual Presentation Course Hours |
| 9. Week | Arrhythmia Mechanisms | Visual Presentation Verbal Expression Course Hours |
| 10. Week | Supraventricular Tachyarrhythmias: Mechanisms, Features, and Management | Course Hours Verbal Expression Visual Presentation |
| 11. Week | Ventricular Tachyarrhythmias: Mechanisms, Features, and Management | Course Hours Visual Presentation Verbal Expression |
| 12. Week | Bradyarrhythmia | Visual Presentation Verbal Expression Course Hours |
| 13. Week | Neural Control of Cardiac Electrical Activity and Cardiac Arrhythmias | Visual Presentation Course Hours Verbal Expression |
| 14. Week | Sex and Age Differences in Arrhythmias | Course Hours Verbal Expression Visual Presentation |
| Cardiac Electrophysiology: From Cell to Bedside. Seventh Edition. 2018 by Elsevier ISBN: 978-0-323-44733-1 |
| Guyton ve Hall Tıbbi Fizyoloji 13. Basım, John E. Hall. Çeviri Editörü: Prof. Dr. Berrak ÇAĞLAYAN YEĞEN, Güneş Tıp Kitabevleri, 2017 Elsevier Limited (Turkey) ISBN: 978-975-277 |
| Cardiovascular Physiology Concepts, New Third Edition, Published by Wolters Kluwer, 2021, ISBN-13: 9781975150075 |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | Measurement Method |
|---|---|---|---|---|---|---|---|
| PY1 | 5 | 5 | 5 | 5 | 5 | 5 | 60 |
| PY2 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY3 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY4 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY5 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY6 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY7 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY8 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY9 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY10 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY11 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY12 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY13 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY14 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY15 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY16 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY17 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 14 | 1 | 14 |
| Research | 14 | 4 | 56 |
| Other Activities | 1 | 4 | 4 |
| Verbal Expression | 14 | 3 | 42 |
| Visual Presentation | 14 | 3 | 42 |
| Midterm 1 | 1 | 2 | 2 |
| Final | 1 | 2 | 2 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
