| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Advanced Cell Physiology | BIO624 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assoc. Prof. Dr. Salih Tunç KAYA |
| Instructors | |
| Assistants | |
| Goals | The aim of this course is to enable students to learn the physiological mechanisms that take place in the cell, the interactions of cells with each other and their environment. |
| Course Content | Homeostasis and cellular physiology, Diffusion and permeability, Osmotic pressure and water movement, Electrical Consequences of Ionic Gradients, Ion Channels, Passive Electrical Properties of Membranes, Generation and propagation of action potential, Ion Channel Diversity, Electrochemical Potential Energy and Transport Processes, Passive Transport, Active Transport, Molecular Motors and Muscle Contraction Mechanism, Muscle Stimulation-Contraction Connection, Muscle Contraction Mechanism |
| Learning Outcomes |
- Learn the structure of the biological membrane and the transport of small and large molecules across the membrane - Learns signal transmission and regulation in the cell - Learn the details of nerve cells and signal transmission |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Introduction: Homeostasis and cellular physiology | Course Hours Visual Presentation |
| 2. Week | Diffusion and permeability | Course Hours Verbal Expression Visual Presentation |
| 3. Week | Osmotic pressure and water movement | Course Hours Verbal Expression Visual Presentation |
| 4. Week | Electrical Consequences of Ionic Gradients | Visual Presentation Course Hours Verbal Expression |
| 5. Week | Ion Channels | Course Hours Verbal Expression Visual Presentation |
| 6. Week | Passive Electrical Properties of Membranes | Course Hours Verbal Expression Visual Presentation |
| 7. Week | Generation and propagation of action potential | Course Hours Visual Presentation Verbal Expression |
| 8. Week | Ion Channel Diversity / Mid Term | Verbal Expression Visual Presentation Course Hours |
| 9. Week | Electrochemical Potential Energy and Transport Processes | Course Hours Verbal Expression Visual Presentation |
| 10. Week | Passive Transport | Course Hours Visual Presentation Verbal Expression |
| 11. Week | Active Transport | Visual Presentation Course Hours Verbal Expression |
| 12. Week | Molecular Motors and Muscle Contraction Mechanism | Course Hours Verbal Expression Visual Presentation |
| 13. Week | Muscle Stimulation-Contraction Connection | Visual Presentation Verbal Expression Course Hours |
| 14. Week | Muscle Contraction Mechanism | Course Hours Verbal Expression Visual Presentation |
| Hücre Fizyolojisi, 2004, Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson, ISBN 0-323-01341-4, Elsevier |
| Hücre Fizyolojisi ve Nörofizyoloji, 2019, Mordecai P. Blaustein, Joseph P. Y. Kao, Donald R. Matteson, Elsevier Health Sciences |
| Cell Physiology, edited by Nicholas Sperelakis 2011 Elsevier Inc. ISBN:978-0-12-387738-3 https://doi.org/10.1016/C2010-0-66479-0 |
| Mechanisms in Cell Physiology, By Michele Mazzanti, Cambridge Scholars Publishing ISBN (10): 1-5275-8248-5 |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | Measurement Method |
|---|---|---|---|---|---|
| PY1 | 5 | 4 | 4 | 4 | 40,60 |
| PY2 | 3 | 3 | 3 | 3 | 40,60 |
| PY3 | 3 | 2 | 2 | 2 | - |
| PY4 | 4 | 4 | 4 | 4 | 40,60 |
| PY5 | 4 | 2 | 3 | 3 | 40,60 |
| PY6 | 5 | 5 | 5 | 5 | 40,60 |
| PY7 | 5 | 4 | 4 | 4 | 40,60 |
| PY10 | 5 | 5 | 5 | 5 | 40,60 |
| PY11 | 5 | 3 | 4 | 3 | 40,60 |
| PY12 | 5 | 4 | 3 | 4 | 40,60 |
| PY13 | 5 | 3 | 5 | 4 | 40,60 |
| PY14 | 4 | 4 | 4 | 4 | 40,60 |
| PY15 | 3 | 2 | 2 | 2 | 40,60 |
| PY16 | 3 | 3 | 3 | 2 | 40,60 |
| PY17 | 5 | 5 | 5 | 5 | 40,60 |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 14 | 1 | 14 |
| Research | 14 | 4 | 56 |
| Other Activities | 1 | 4 | 4 |
| Verbal Expression | 14 | 3 | 42 |
| Visual Presentation | 14 | 3 | 42 |
| Midterm 1 | 1 | 2 | 2 |
| Final | 1 | 2 | 2 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
