| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Molecular Genetics | BIO308 | 3 + 2 | 4.0 | 6.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Prof. Dr. MERAL KEKEÇOĞLU |
| Instructor(s) | |
| Assistants | |
| Goals | To learn the structure and function of hereditary materials. To comprehend the steps of the period of inheritance of the information from gene to protein. |
| Course Content | Genes, genes genome, gene number, repeats, gene families, mutagens, mutation, repair mechanisms, Protein Synthesis, Using the genetic code, the operon, transposons, oncogenes, cancer, cell cycle, methods in molecular genetic studies. |
| Learning Outcomes |
- Comprehend the principles of components having role in heredity - Learn the molecular basis of heredity - Identify the species, comprehend the structure and function of living organisms. - Gain the ability to identify a scientific study. Describe and solve problems. - Learn modern techniques and biological analysis methods used in the laboratory and gain the ability to apply them. - Learn the origin of liveliness, the process of development of living organisms and the term of evolution. In this concept, interpret the diversity of organisms. - Acquire professional knowledge to communicate with fellows. Gain awareness of professional and ethical responsibility. - Work independently and in collaboration within a team in an advanced study. - Manage to access the information. Gain the ability to use the databases and information systems. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Genes and DNA | Research Other Activities Course Hours Preparation, After Class Study |
| 2. Week | Segmented genes-Exons, introns and restriction enzymes | Research Other Activities Preparation, After Class Study Course Hours |
| 3. Week | Content and sequence of genome, gene numbers | Other Activities Course Hours Preparation, After Class Study Research |
| 4. Week | Gene clusters and repeats | Course Hours Preparation, After Class Study Research Other Activities |
| 5. Week | Replication of DNA | Course Hours Preparation, After Class Study Research Other Activities |
| 6. Week | DNA repair mechanisms | Course Hours Preparation, After Class Study Research Other Activities |
| 7. Week | Transposons, retroviruses and retrotransposons | Course Hours Research Preparation, After Class Study Other Activities |
| 8. Week | RNA and expression | Other Activities Preparation, After Class Study Research Course Hours |
| 9. Week | Midterm | Preparation, After Class Study Research Other Activities Course Hours |
| 10. Week | RNA splicing and processing | Preparation, After Class Study Research Other Activities Course Hours |
| 11. Week | Promoters and enhancers | Preparation, After Class Study Research Other Activities Course Hours |
| 12. Week | Protein synthesis | Preparation, After Class Study Research Course Hours Other Activities |
| 13. Week | Protein synthesis | |
| 14. Week | Epigenetics, posttranscriptional and posttranslational modifications | Preparation, After Class Study Other Activities Research Course Hours |
| Lecture notes |
| Krebs JE, Goldstein ES, Kilpatrick. 2011. Lewin’s Genes X, John’s and Bartlett publishers, USA |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | DK7 | DK8 | DK9 | Measurement Method |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PY1 | 3 | 3 | 2 | 1 | 3 | 5 | 2 | 4 | 4 | 3 | 40,60 |
| PY2 | 3 | 3 | 1 | 1 | 3 | 4 | 3 | 4 | 4 | 4 | - |
| PY3 | 3 | 3 | 2 | 1 | 4 | 5 | 4 | 4 | 4 | 5 | - |
| PY4 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | 40,60 |
| PY5 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | 40,60 |
| PY6 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | 40,60 |
| PY7 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY8 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY9 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY10 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY11 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY12 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY13 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY14 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | - |
| PY15 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | 40,60 |
| PY16 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | 40,60 |
| PY17 | 4 | 3 | 2 | 1 | 4 | 5 | 5 | 5 | 4 | 4 | 40,60 |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 28 | 28 |
| Homework 2 | 1 | 28 | 28 |
| Final | 1 | 2 | 2 |
| Practice | 14 | 2 | 28 |
| Practice End-Of-Term | 1 | 23 | 23 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 153 | ||
| ECTS Credit of the Course | 6.0 | ||
