| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Cardiac Electrophysiology | BIO780 | 3 + 0 | 3.0 | 7.5 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to Face |
| Course Coordinator |
Assoc. Prof. Dr. Salih Tunç KAYA |
| Instructors | |
| Assistants | |
| Goals | The aim of this course is to enable students to comprehend the electrical activity of the heart muscle at the cellular and molecular level and to define the rhythm disorders observed because of the disruption of electrical activity. |
| Course Content | Cardiomyocyte Electrical Function, Cardiac Impulse Initiation and Propagation, Structural and Molecular Bases of Cardiac Ion Channel Function, Models of Cardiac Excitation, Normal Electrocardiogram, Electrocardiographic Interpretation of Heart Muscle and Coronary Blood Flow Disorders: Calculations with Vectors, Cardiac Arrhythmias and Interpretations Based on Electrocardiography, Myocardial Ischemia and Reperfusion Injury, Arrhythmia Mechanisms, Supraventricular Tachyarrhythmias: Mechanisms, Features, and Management, Ventricular Tachyarrhythmias: Mechanisms, Features, and Management, Bradyarrhythmia, Neural Control of Cardiac Electrical Activity and Cardiac Arrhythmias, Sex and Age Differences in Arrhythmias |
| Learning Outcomes |
- Knows the Electrical Function of the Heart. - Interpret the contraction of the heart muscle based on Electrocardiography - Knows and interprets Cardiac Arrhythmias based on Electrocardiography - Will be able to explain the cellular and molecular mechanism of cardiac arrhythmias - Will be able to explain the cellular mechanism of myocardial ischemia and perfusion injury and the arrhythmias observed because of damage. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Cardiomyocyte Electrical Function | |
| 2. Week | Cardiac Impulse Initiation and Propagation | |
| 3. Week | Structural and Molecular Bases of Cardiac Ion Channel Function | |
| 4. Week | Models of Cardiac Excitation | |
| 5. Week | Normal Electrocardiogram | |
| 6. Week | Electrocardiographic Interpretation of Heart Muscle and Coronary Blood Flow Disorders: Calculations with Vectors | |
| 7. Week | Cardiac Arrhythmias and Interpretations Based on Electrocardiography | |
| 8. Week | Myocardial Ischemia and Reperfusion Injury / Mid Term | |
| 9. Week | Arrhythmia Mechanisms | |
| 10. Week | Supraventricular Tachyarrhythmias: Mechanisms, Features, and Management | |
| 11. Week | Ventricular Tachyarrhythmias: Mechanisms, Features, and Management | |
| 12. Week | Bradyarrhythmia | |
| 13. Week | Neural Control of Cardiac Electrical Activity and Cardiac Arrhythmias | |
| 14. Week | Sex and Age Differences in Arrhythmias |
| Cardiac Electrophysiology: From Cell to Bedside. Seventh Edition. 2018 by Elsevier ISBN: 978-0-323-44733-1 |
| Guyton ve Hall Tıbbi Fizyoloji 13. Basım, John E. Hall. Çeviri Editörü: Prof. Dr. Berrak ÇAĞLAYAN YEĞEN, Güneş Tıp Kitabevleri, 2017 Elsevier Limited (Turkey) ISBN: 978-975-277 |
| Cardiovascular Physiology Concepts, New Third Edition, Published by Wolters Kluwer, 2021, ISBN-13: 9781975150075 |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | Measurement Method |
|---|---|---|---|---|---|---|---|
| PY1 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY2 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY3 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY4 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY5 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY6 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY7 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY8 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY9 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY10 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY11 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY12 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY13 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY14 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY15 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY16 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY17 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 14 | 2 | 28 |
| Research | 14 | 2 | 28 |
| Verbal Expression | 14 | 1 | 14 |
| Visual Presentation | 14 | 2 | 28 |
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 4 | 4 |
| Homework 2 | 1 | 1.25 | 1.25 |
| Final | 1 | 2 | 2 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 191.25 | ||
| ECTS Credit of the Course | 7.5 | ||
