| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Biology of Aging | BIO556 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to Face |
| Course Coordinator |
Assoc. Prof. Dr. Salih Tunç KAYA |
| Instructors | |
| Assistants | |
| Goals | The aim of this course is to provide students with knowledge and understanding of the changes in physiological systems, related theories and mechanisms caused by both organism and cell aging. |
| Course Content | Evolutionary Theories of Aging Studies, Model Organisms in Aging Studies, Intraspecies And Interspecies Metabolic Rate and Lifespan, Cellular Aging, Destruction and Repair, Signaling Systems in Aging, Systemic Changes in The Body Due to Aging, Diseases Related to Aging; Connective Tissue and Skeletal System, Diseases Related to Aging; Cardiovascular System, Diseases Related to Aging; Endocrine System, Diseases Related to Aging; Nervous System, Diseases Related to Aging; Respiratory System, Diseases Related to Aging; Urinary System, Diseases Related to Aging; Gastrointestinal System, Nutrient Restriction and Aging |
| Learning Outcomes |
- Will be able to define evolutionary theories of aging studies. - Knows the differences in metabolic rate and life span within and between species. - Will be able to explain the determination of aging rate using different environmental stress sources. - Will be able to explain the relationship between aging and physiological systems. - Has knowledge about the effects of aging on physiological systems and diseases. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Evolutionary Theories of Aging Studies | |
| 2. Week | Model Organisms in Aging Studies | |
| 3. Week | Intraspecies And Interspecies Metabolic Rate and Lifespan | |
| 4. Week | Cellular Aging, Destruction and Repair | |
| 5. Week | Signaling Systems in Aging | |
| 6. Week | Systemic Changes in The Body Due to Aging | |
| 7. Week | Diseases Related to Aging; Connective Tissue and Skeletal System | |
| 8. Week | Diseases Related to Aging; Cardiovascular System / Mid Term | |
| 9. Week | Diseases Related to Aging; Endocrine System | |
| 10. Week | Diseases Related to Aging; Nervous System | |
| 11. Week | Diseases Related to Aging; Respiratory System | |
| 12. Week | Diseases Related to Aging; Urinary System | |
| 13. Week | Diseases Related to Aging; Gastrointestinal System | |
| 14. Week | Nutrient Restriction and Aging |
| • Guyton ve Hall Tıbbi Fizyoloji 13. Basım, John E. Hall. Çeviri Editörü: Prof. Dr. Berrak ÇAĞLAYAN YEĞEN, Güneş Tıp Kitabevleri, 2017 Elsevier Limited (Turkey) ISBN: 978-975-277 |
| • Arking, Robert; "The Biology of Aging: Observations and Principles" (2006). Oxford University Press, Oxford. ISBN10: 0195167392 |
| • Rose, Michael; "Evolutionary Biology of Aging" (1991). Oxford University Press, New York. |
| • Hayflick, Leonard; "How and Why We Age" (1994). Ballantine Books, NY. ISBN 10: 0345401557 |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | Measurement Method |
|---|---|---|---|---|---|---|---|
| PY1 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY2 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY3 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY4 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY5 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY6 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY7 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY8 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY9 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY10 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY11 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY12 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY13 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| PY14 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY15 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY16 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY17 | 5 | 5 | 5 | 5 | 5 | 5 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 14 | 3 | 42 |
| Research | 14 | 3 | 42 |
| Verbal Expression | 14 | 1 | 14 |
| Visual Presentation | 14 | 1 | 14 |
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 4 | 4 |
| Final | 1 | 2 | 2 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
