| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Artificial Membranes, Liposomes and Their Applications in Biological Sciences | BIO555 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assoc. Prof. Dr. Gülgün ÇAKMAK ARSLAN |
| Instructors | |
| Assistants | |
| Goals | The aim of this lecture is to learn about the structure, functions, physicochemical characteristics of artificial membranes, the types of model membranes and the applications of model membranes in medicine and biology. |
| Course Content | The structure and functions of artificial membranes, Types of artificial membranes, Preparation methods of artificial membranes, Physicochemical characteristics of artificial membranes (phase transition, fluidity, dynamic, permeability) Osmotic features, stability of liposome structures, The procedures of encapsulation, Applications of liposomes in biological research, Applications of liposomes in medical research, Liposomal therapy and its applications, Applications of liposomes in drug-membrane interactions and the methods used in research |
| Learning Outcomes |
- To understand the structure and functions of artificial membranes, to get knowledge about the types of artificial membranes. - To learn the preparation methods of artificial membranes. - To have knowledge about the phase transition, fluidity, dynamic, permeability, osmotic features, stability of liposome structures - To learn the procedures of encapsulation. - To understand the applications of liposomes in medical and biological research, liposomal therapy and its applications. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | The structure and functions of artificial membranes | Research Course Hours Other Activities |
| 2. Week | Types of artificial membranes | Course Hours Research Other Activities |
| 3. Week | Preparation methods of artificial membranes | Course Hours Other Activities Research |
| 4. Week | DPhysicochemical characteristics of artificial membranes (phase transition, fluidity) | Other Activities Research Course Hours |
| 5. Week | Physicochemical characteristics of artificial membranes (dynamic, permeability) | Research Other Activities Course Hours |
| 6. Week | Osmotic features, stability of liposome structures | Other Activities Research Course Hours |
| 7. Week | The procedures of encapsulation | Course Hours Research Other Activities |
| 8. Week | Applications of liposomes in biological research | Other Activities Research Course Hours |
| 9. Week | Mid-term | Course Hours |
| 10. Week | Applications of liposomes in medical research | Other Activities Research Course Hours |
| 11. Week | Liposomal therapy and its applications | Course Hours Research Other Activities |
| 12. Week | Applications of liposomes in drug-membrane interactions and the methods used in research | Course Hours Other Activities Research |
| 13. Week | Presentation and discussion about scientific papers | Research Other Activities Course Hours |
| 14. Week | Presentation and discussion about scientific papers | Research Course Hours Other Activities |
| 1- Petty, H., L. 1993. Molecular Biology of Membranes (Structure and Function), 1993, Plenum Press, New York. |
| 2- Stillwell, W. An Introduction to Biological Membrane:From Bilayers to Rafts, 2013, Elsevier |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | Measurement Method |
|---|---|---|---|---|---|---|---|
| PY1 | 5 | 5 | 4 | 4 | 5 | 5 | - |
| PY2 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY3 | 4 | 2 | 5 | 3 | 5 | 3 | - |
| PY4 | 4 | 2 | 5 | 5 | 4 | 4 | - |
| PY5 | 4 | 4 | 4 | 4 | 4 | 5 | - |
| PY6 | 2 | 2 | 2 | 2 | 2 | 4 | - |
| PY7 | 2 | 2 | 2 | 2 | 3 | 3 | - |
| PY8 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY9 | 4 | 2 | 3 | 3 | 5 | 5 | - |
| PY10 | 3 | 2 | 3 | 3 | 3 | 5 | - |
| PY11 | 2 | 2 | 2 | 2 | 2 | 2 | - |
| PY12 | 3 | 2 | 2 | 4 | 4 | 5 | - |
| PY13 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY14 | 2 | 1 | 1 | 1 | 1 | 4 | - |
| PY15 | 2 | 1 | 1 | 1 | 1 | 4 | - |
| PY16 | 2 | 2 | 2 | 2 | 2 | 3 | - |
| PY17 | 3 | 3 | 3 | 3 | 3 | 5 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 3 | 3 |
| Homework 1 | 1 | 50 | 50 |
| Homework 2 | 1 | 50 | 50 |
| Final | 1 | 3 | 3 |
| Practice End-Of-Term | 1 | 42 | 42 |
| Classroom Activities | 14 | 4 | 56 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
