| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Medican Genetics | BIO549 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Prof. Dr. Görkem DÜLGER |
| Instructors | |
| Assistants | |
| Goals | To comprehend basic mechanism of heredity and hereditary disorders. |
| Course Content | Human genome, Structure of genes and chromosomes, Chromosomal basis of inheritance, Principles of clinical cytogenetics and chromosomal disorders, Single gene inheritance patterns, Genetic variation in humans: mutation and polymorphism Genetic changes in human populations and their place in practice, Gene mapping, Human Genome Project, Genetics of multifactorial inherited diseases, Molecular and biochemical basis of genetic diseases Immune system genetics, Genetic structure of cancer, Genetic structure of cancer, Genetic aspects of development |
| Learning Outcomes |
- Learn the classical and modern methods used in human genetics - Comprehend the application of these methods - Understand how the hereditary information is used for diagnosis and treatment of hereditary disorders |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Human genome: Structure of genes and chromosomes | |
| 2. Week | Chromosomal basis of heredity | |
| 3. Week | Principles of clinical cytogenetics and chromosomal abnormalities | |
| 4. Week | Single gene inheritance | |
| 5. Week | Genetic variations in humans: mutations and polymorphisms | |
| 6. Week | Genetic variations in human populations | |
| 7. Week | Gene mapping | |
| 8. Week | Human genome project | |
| 9. Week | Mid-Term | |
| 10. Week | Principles of multifactorial inheritance | |
| 11. Week | The molecular and biochemical basis of genetic diseases | |
| 12. Week | Genetics of immunity | |
| 13. Week | Genetics of cancer | |
| 14. Week | Genetics of cancer-2 |
| • Thompson&Thompson Genetics in Medicine, R Nussbaum, RR. McInnes, HF Willard,2007 |
| • www.ncbi.nlm.nih.gov |
| • www.ensembl.org |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | Measurement Method |
|---|---|---|---|---|---|
| PY1 | 5 | 0 | 0 | 0 | - |
| PY2 | 5 | 0 | 0 | 0 | - |
| PY3 | 5 | 0 | 0 | 0 | - |
| PY4 | 5 | 0 | 0 | 0 | - |
| PY6 | 4 | 0 | 0 | 0 | - |
| PY7 | 4 | 0 | 0 | 0 | - |
| PY8 | 3 | 0 | 0 | 0 | - |
| PY9 | 3 | 0 | 0 | 0 | - |
| PY10 | 5 | 0 | 0 | 0 | - |
| PY11 | 3 | 0 | 0 | 0 | - |
| PY12 | 4 | 0 | 0 | 0 | - |
| PY13 | 4 | 0 | 0 | 0 | - |
| PY14 | 3 | 0 | 0 | 0 | - |
| PY15 | 4 | 0 | 0 | 0 | - |
| PY16 | 5 | 0 | 0 | 0 | - |
| PY17 | 5 | 0 | 0 | 0 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 14 | 3 | 42 |
| Research | 14 | 3 | 42 |
| Verbal Expression | 14 | 1 | 14 |
| Visual Presentation | 14 | 1 | 14 |
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 4 | 4 |
| Final | 1 | 2 | 2 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
