| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Research Methods in Cytogenetics | BIO546 | 2 + 2 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assoc. Prof. Dr. Pınar GÖÇ RASGELE |
| Instructors | |
| Assistants | |
| Goals | This instruction aims to teach methods of cytogenetics and to use this methods in various application scope |
| Course Content | Defining the molecular organization of the chromosome, karyotype analysis from a variety of plants and animal cells, Explaining different methods of in vivo and in vitro cytogenetic investigations. |
| Learning Outcomes |
- To comprehend fundamental knowledge of cytogenetic - To evaluate with cytogenetic methods knowledge about cytology and genetics - To own knowledge about morphologic properties and number, size of chromosomes - To prepare karyotype and idiogram - To learn the most suitable methods for chromosome observation - To make statistical evaluation concern with mitotic index and chromosome abnormalities - To gain oral and written communication skills |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Introduction to the Cytogenetic | Preparation, After Class Study Other Activities Research |
| 2. Week | Structure of chromosomes | Research Preparation, After Class Study Other Activities |
| 3. Week | B chromosomes and giant chromosomes | Research Other Activities Preparation, After Class Study |
| 4. Week | Structural chromosome changes | Preparation, After Class Study Other Activities Research |
| 5. Week | Numerical chromosome changes | Other Activities Preparation, After Class Study Research |
| 6. Week | Cell division, mitosis | Other Activities Preparation, After Class Study Research |
| 7. Week | Meiosis | Preparation, After Class Study Research Other Activities |
| 8. Week | Mid Term | Research Other Activities Preparation, After Class Study |
| 9. Week | Preparation techniques for cytogenetic observations in plants | Preparation, After Class Study Research Other Activities |
| 10. Week | Preparation techniques for cytogenetic observations in human blood | Research Other Activities Preparation, After Class Study |
| 11. Week | Preparation techniques for cytogenetic observations in experimental animals | Research Other Activities Preparation, After Class Study |
| 12. Week | Preparation techniques for cytogenetic observations in honeybees | Preparation, After Class Study Research Other Activities |
| 13. Week | Karyotype and idiogram analysis | Other Activities Preparation, After Class Study Research |
| 14. Week | Banding techniques | Other Activities Research Preparation, After Class Study |
| Sitogenetik. Prof.Dr.Mehmet Topaktaş, Prof.Dr.Eyyüp Rencüzoğulları. Nobel yayın dağıtım.2010 |
| Tıbbi genetik. Prof.Dr.Nurettin Başaran. Güneş ve Nobel tıp kitabevi |
| Human Cytogenetics. DE Rooney, BH Czepulkowski. IRL PressMedical |
| Genetics. Gardner.Klug, W. S., Cummings, M.R. Spencer, A.C. (2006). |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | DK7 | Measurement Method |
|---|---|---|---|---|---|---|---|---|---|
| PY1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY2 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY5 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY6 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY7 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY8 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY9 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY10 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY11 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY12 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY13 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY14 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY15 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY16 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY17 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 50 | 50 |
| Homework 2 | 1 | 50 | 50 |
| Final | 1 | 2 | 2 |
| Practice End-Of-Term | 1 | 45.25 | 45.25 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 191.25 | ||
| ECTS Credit of the Course | 8.0 | ||
