| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Molecular Structure and Function of Biological Membranes | BIO520 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assoc. Prof. Dr. Gülgün ÇAKMAK ARSLAN |
| Instructors | |
| Assistants | |
| Goals | The aim of this lecture is to get detailed knowledge about the molecular structure, composition, functions and physicochemical properties of biological membranes. |
| Course Content | An introduction to biological membranes, Membrane lipids, Membrane proteins, Membrane carbohydrates and cytoskeletal components, The functions of biological membranes (proton pumping, photosynthetic membranes, mitochondrial membranes), Membrane receptors , Transport across the membrane, Physicochemical characteristics of biological membranes (phase transition, fluidity), Physicochemical characteristics of biological membranes (dynamic, permeability) Membrane isolation techniques, The biophysical techniques used in biological membrrane studies |
| Learning Outcomes |
- To understand molecular structure of biological membranes. - To learn the molecules in biological membranes. - To understand the functions of biological membranes - To get knowledge about membrane transportation. - To understand the physical characteristics of biological membranes. - To learn the membrane isolation techniques. - To understand the biophysical techniques used in biological membrane studies. - 8. To make students follow current developments in this field of research by reading/discussing new research papers and to evaluate. - To be able to share information about biological techniques by oral and written language. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | An introduction to biological membranes | Other Activities Course Hours Research |
| 2. Week | Membrane lipids | Other Activities Research Course Hours |
| 3. Week | Membrane proteins | Course Hours Other Activities Research |
| 4. Week | Membrane carbohydrates and cytoskeletal components | Research Other Activities Course Hours |
| 5. Week | The functions of biological membranes (proton pumping, photosynthetic membranes, mitochondrial membranes) | Other Activities Research Course Hours |
| 6. Week | Membrane receptors | Course Hours Research Other Activities |
| 7. Week | Transport across the membrane | Course Hours Research Other Activities |
| 8. Week | Mid-term exam | Course Hours |
| 9. Week | Physicochemical characteristics of biological membranes (phase transition, fluidity) | Research Course Hours Other Activities |
| 10. Week | Physicochemical characteristics of biological membranes (dynamic, permeability) | Course Hours Research Other Activities |
| 11. Week | Membrane isolation techniques | Other Activities Course Hours Research |
| 12. Week | The biophysical techniques used in biological membrrane studies | Research Course Hours Other Activities |
| 13. Week | Presentation and discussion about scientific papers | Course Hours Research Other Activities |
| 14. Week | Presentation and discussion about scientific papers | Course Hours Research Other Activities |
| Yeagle, P. 2000. The Structure of Biological Membranes, CRC Press LCL. |
| Petty, H., L. 1993. Molecular Biology of Membranes (Structure and Function), Plenum Press, New York. |
| Stillwell, W. 2013. An Introduction to Biological Membrane:From Bilayers to Rafts, Elsevier. |
| Heinburg, T. 2007. Thermal Biophysics of Membrane, Wiley-VCH, Weinheim. |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | DK7 | DK8 | DK9 | Measurement Method |
|---|---|---|---|---|---|---|---|---|---|---|---|
| PY1 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY2 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | - |
| PY3 | 4 | 2 | 2 | 3 | 3 | 3 | 5 | 5 | 4 | 4 | - |
| PY4 | 3 | 2 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 5 | - |
| PY5 | 3 | 2 | 2 | 2 | 2 | 2 | 5 | 5 | 5 | 3 | - |
| PY6 | 3 | 2 | 2 | 2 | 2 | 2 | 4 | 4 | 4 | 4 | - |
| PY7 | 2 | 1 | 1 | 1 | 1 | 3 | 3 | 3 | 4 | 4 | - |
| PY8 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 5 | - |
| PY9 | 2 | 1 | 1 | 1 | 1 | 3 | 3 | 2 | 2 | 4 | - |
| PY11 | 2 | 1 | 1 | 1 | 1 | 2 | 2 | 2 | 2 | 2 | - |
| PY12 | 3 | 2 | 2 | 2 | 2 | 2 | 3 | 3 | 3 | 4 | - |
| PY13 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | - |
| PY14 | 2 | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 | 1 | - |
| PY15 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 3 | 4 | - |
| PY16 | 3 | 2 | 2 | 2 | 2 | 2 | 3 | 4 | 4 | 4 | - |
| PY17 | 3 | 2 | 2 | 2 | 2 | 2 | 4 | 4 | 5 | 3 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 56 | 56 |
| Homework 2 | 1 | 56 | 56 |
| Final | 1 | 2 | 2 |
| Practice End-Of-Term | 1 | 46 | 46 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
