| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Fundamentals of Genetics | BIO307 | 3 + 2 | 4.0 | 5.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assoc. Prof. Dr. Gülgün ÇAKMAK ARSLAN |
| Instructors | |
| Assistants | |
| Goals | To learn the basic concepts of principles of heredity. |
| Course Content | History of genetics, Mendelian genetics, monohybrid crosses, the effects of genes according to the classification of Heredity, the cytological basis of chromosome molecular structure, meiosis, meiosis and mitosis comparison; dihybrit inheritance, gametes Zygote combinations, allele non-gene interactions between, the degree of compliance and contingency rules, gene commitment (linkage), and crossing over and chromosome maps, bacterial genes in commitment and mapping studies, the virus genes in adherence studies, multiple alleles are, pseudoallel, and blood group inheritance, polygenic inheritance, quantitative genetics, sex determination, sex-linked inheritance, sex-linked lathel genes , the genes affected by the gender; chromosomal aberrations chromosome changes in the structure of, population genetics, Hardy-Weinberg rule, immigration selection, mutation. |
| Learning Outcomes |
- To be able to explain the structure and functions of chromosomes - To be able to explain the types and basic steps of cell division - To be able to explain the basic mechanisms of heredity - To be able to understand the basic principles of Mendelian and non-Mendelian inheritance - To be able to make probability and statistical calculations related to genetics - Gain information about chromosomal variations, gene connections and crossing over mechanisms. - Understanding population genetics. - To be able to establish the relationship between genetics and evolution |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Cell division and chromosomes | Other Activities Course Hours |
| 2. Week | Principles of Mendelian genetics: Monohybrid, dihybrid and trihybrid crosses | Course Hours Other Activities |
| 3. Week | Genetics and probability: Chi square and pedigree analysis | Other Activities Course Hours |
| 4. Week | Deviation from Mendelain ratios and X-linked heredity | Course Hours Other Activities |
| 5. Week | Genetic linkage and independent assortment | Course Hours Other Activities |
| 6. Week | Crossing-over and chromosome maps | Other Activities Course Hours |
| 7. Week | Expression of genetic analysis | Course Hours Other Activities |
| 8. Week | Mid term | |
| 9. Week | Extranuclear heredity | Course Hours Other Activities |
| 10. Week | Chromosomal variations | Preparation, After Class Study Research Other Activities Course Hours |
| 11. Week | Sex determination and sex chromosomes | Course Hours Preparation, After Class Study Research Other Activities |
| 12. Week | Population genetics | Research Other Activities Course Hours Preparation, After Class Study |
| 13. Week | Population Genetics | |
| 14. Week | Quantitative traits and evolution | Course Hours Preparation, After Class Study Research Other Activities |
| Klug, W. S., Cummings, M.,R., Genetik Kavramlar(Çeviri Editörü, Öner, C), Palme yayıncılık, Ankara, 2002. |
| Yıldırım A., Kandemir N., Genetik, Nobel yayınevi, Ankara, 2008. |
| Soysal M. 2000. Genetik-I “ Soya çekim Bilgisi” yayın no: 74, ders notu no:135, 2000. |
| Temizkan G., 1999. Genetik II, İstanbul Üniversitesi Fen Fak |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | DK7 | DK8 | Measurement Method |
|---|---|---|---|---|---|---|---|---|---|---|
| PY1 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY4 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY5 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY6 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY7 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY8 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY9 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY10 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY11 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY12 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY13 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY14 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY15 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY16 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| PY17 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 2 | 2 |
| Homework 1 | 1 | 16 | 16 |
| Homework 2 | 1 | 16 | 16 |
| Final | 1 | 2 | 2 |
| Practice | 14 | 2 | 28 |
| Practice End-Of-Term | 1 | 21.5 | 21.5 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 127.5 | ||
| ECTS Credit of the Course | 5.0 | ||
