| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Pahrmaceutical Technology III Practic | ECZ497 | 7. Semester | 0 + 4 | 2.0 | 3.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | Face to face |
| Course Coordinator |
Assist. Prof. Dr. Miray İLHAN |
| Instructors | |
| Assistants | |
| Goals | Teaching of formulations design, production technologies and quality control tests of solid dosage forms to students, Teaching the formulation strategies of new drug delivery systems, Instruction of stability studies and shelf life calculation |
| Course Content | Micromeritic, Powder Preparations (Package, Granule, Effervescent Granule, Granule Controls), Capsule (Hard and Soft), Lozenges (Hard/Soft/Chewable Lozenges), Tablet Formulations Prepared by Direct Pressing, Tablet Formulations Prepared by Wet Granulation, Effervescent Tablet, Chewable Tablet, Coating of Tablets - Dragee Manufacturing, Controls on Tablets (Dissolution Test), Particulate Drug Delivery Systems (Microcapsule, Bead Type Formulations and Nanoparticle Type Formulations), Stability Studies |
| Learning Outcomes |
- Controls the dosage of drugs - Makes pharmaceutical calculations about solid dosage forms, design, produce and carry out product improvement studies. - Makes the necessary quality control processes in solid dosage forms. - Prepares the formulation of particulate drug delivery systems. - Labels drugs in a warning / informative way. - Performs accelerated stability studies and calculates the shelf life with Arrhenius equation. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Powder Technology and Micromeritics | |
| 2. Week | Powder Preparations (Package, Granules, Effervescent Granules, Granule Controls) | |
| 3. Week | Capsules (Hard and Soft) | |
| 4. Week | Pastilles (Hard / Soft / Chewable Pastilles) | |
| 5. Week | Tablet Formulations Prepared by Direct Compression | |
| 6. Week | Tablet Formulations Prepared with Wet Granulation | |
| 7. Week | Tablet Formulations Prepared with Wet Granulation | |
| 8. Week | Midterm exam | |
| 9. Week | Effervescent Tablet, Chewable Tablet | |
| 10. Week | Tablet Coating - Dragee Manufacturing | |
| 11. Week | Controls Made on Tablets (Dissolution Test) | |
| 12. Week | Particulate Drug Delivery Systems (Microcapsule, Bead and Nanoparticle Type Formulations) | |
| 13. Week | Stability Tests | |
| 14. Week | Practice | |
| 15. Week | Practice |
| Asuman Bozkır, Ayşegül Karataş, Canan Hasçiçek, Kandemir Canefe, Müge Kılıçarslan, Nilüfer Tarımcı, Nilüfer Yüksel, Nurşin Gönül, Nurten Özdemir, Tamer Baykara, Tangül Kılınç-Şen, Tansel Çomoğlu, Farmasötik Teknoloji Deneysel Uygulamalar Kitabı, Ankara Üniversitesi Basımevi, 2007. |
| Modern Farmasötik Teknoloji, F. Acartürk, İ. Ağabeyoğlu, N. Çelebi, T. Değim, Z. Değim, T. Doğanay, S. Takka, F. Tırnaksız, Türk Eczacılar Birliği, Eczacılık Akademisi Yayını Yayın No: 1, Ankara, 2007. |
| Farmasötik Teknoloji, Temel Konular ve Dozaj Şekilleri, Ed.: Ayla Z. Gürsoy, Kontrollü Salım Sistemleri Derneği Yayını No: 2, İstanbul, 2004. |
| Encyclopedia of Pharmaceutical Science and Technology, Six Volume Set, Ed.: James Swarbrick, CRC Press, Tayor and Francis Group, USA, 2013. |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 1 | 1 |
| Final | 1 | 1 | 1 |
| Classroom Activities | 14 | 4 | 56 |
| Total Workload | 58 | ||
| ECTS Credit of the Course | 3.0 | ||
