| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Pharmaceutical Chemistry IV Laboratory | ECZ492 | 8. Semester | 0 + 4 | 2.0 | 2.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | face to face |
| Course Coordinator |
Assist. Prof. Dr. Bahadır BÜLBÜL |
| Instructors | |
| Assistants | |
| Goals | The purpose of this course is to give the principles and applications of the chemical and instrumental techniques such as ultraviolet, infrared, nuclear magnetic resonance and mass spectroscopic used in qualitative analysis and structural elucidation of drugs. |
| Course Content | |
| Learning Outcomes |
- How to analyse the functional groups using chemical tests - Instrumental techniques such as UV, IR, NMR and mass used in structural elucidation of organic compounds - The ability of structural elucidation of molecule using chemical and spectral data at the same time - How to reach to the structure of unknown compound by means of spectral and chemical reactions |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Demonstration (Chemical identification reactions) | |
| 2. Week | Demonstration (Chemical identification reactions) and Elemental Analysis | |
| 3. Week | Chemical characterization of organic compounds containing oxygen | |
| 4. Week | Chemical characterization of organic compounds containing nitrogen and sulfur | |
| 5. Week | Demonstration (Introduction to spectroscopy and UV, IR) | |
| 6. Week | Demonstration (I1H-NMR) | |
| 7. Week | Demonstration (13C-NMR and Mass) | |
| 8. Week | Investigation of the spectrum of unknown compound | |
| 9. Week | Investigation of the spectrum of unknown compound | |
| 10. Week | Unknown analysis | |
| 11. Week | Unknown analysis | |
| 12. Week | Unknown analysis | |
| 13. Week | Homework and Discussion | |
| 14. Week | Homework and Discussion |
| Silverstein RM, ?Spectrophotometric Identification of Organic Compounds? New York, 1987. |
| Creswel CJ, ?Spectral Analysis of Organic Compounds? Minneapolis, 1972. |
| Ergenç N, ?İlaçların Tanınması ve Kantitatif Tayini ?, İstanbul 1999. |
| Yıldız A, ?Enstrumantal Analiz Yöntemleri? Ankara, 1997. |
| Williams DH, Fleming I, ?Spectroscopic Methods in Organic Chemistry? London, 1995. |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 1 | 1 |
| Homework 1 | 10 | 1 | 10 |
| Final | 1 | 2 | 2 |
| Practice | 1 | 10 | 10 |
| Classroom Activities | 14 | 2 | 28 |
| Total Workload | 51 | ||
| ECTS Credit of the Course | 2.0 | ||
