| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Pharmaceutical Chemistry III | ECZ405 | 7. Semester | 3 + 0 | 3.0 | 3.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | face to face |
| Course Coordinator |
Assist. Prof. Dr. Bahadır BÜLBÜL |
| Instructors | |
| Assistants | |
| Goals | The aim of this course is to give the students the basic theoretical knowledge of structures, synthesis, structure-activity relationships, mode of action, biotransformations and pharmacological activities of chemotherapeutic agents. |
| Course Content | |
| Learning Outcomes |
- The student who completes this course learn: 1. Structures, 2. Methods of synthesis, 3. Structure-activity relationships 4. Mode of actions, 5. Bitransformations and, 6. Uses of antiseptic, disinfectant, antiprotozoal (antimalarial, antiemobic, antileishmanial, antitrichomonal, antitrypanosomal), anti-ectoparasitic, antihelmintic, antifungal, antimycobacterial, antibacterial, antineoplastic and antiviral compounds. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Introduction to chemotherapy, antiseptic and disinfectans | |
| 2. Week | Introduction of antiprotozoal drugs, antimalarial drugs | |
| 3. Week | Antiaemobic, antileishmanial, antitricomonal, antitrypanosomal and antihelmintic drugs | |
| 4. Week | Anti-ectoparasitic and antifungal drugs | |
| 5. Week | Antimycobacterial drugs | |
| 6. Week | Antibacterial drugs | |
| 7. Week | Antibacterial drugs | |
| 8. Week | Antibiotics | |
| 9. Week | Antibiotics | |
| 10. Week | Antibiotics and introduction to antineoplastic drugs | |
| 11. Week | Antineoplastic drugs | |
| 12. Week | Antineoplastic drugs | |
| 13. Week | Antiviral drugs | |
| 14. Week | Antiviral drugs |
| Akgün, H., Balkan, A., Bilgin, A.A., Çalış, Ü., Dalkara, S., Erdoğan, H., Erol, D.D., Ertan, M., Gökhan, N., Özkanlı, F., Palaska, E., Saraç, S., Şafak, C., Tozkoparan, B.: Farmasötik Kimya, Ankara, 2004. |
| Lemke, T.L., Williams, D.A., Roche, V.F., Zito, S.W., ?Foye?s Principles of Medicinal Chemistry?, 6th ed., L,ippincott Williams & Wilkins, 2008. |
| Delgado, J.N., Remers, W.A. (ed), Wilson & Gisvold?s Textbook of Organic Medicinal and Pharmaceutical Chemistry, 9th ed., Lippincott, Philadelphia, 1991. |
| Patrick, G.L., An Introduction to Medicinal Chemistry, Oxford University Press, Oxford, 1999. |
| Wolff, M.E., ?Burger?s Medicinal Chemistry and Drug Discovery?, Volume I-V, 4th edition, Wiley-Interscience, 1980-97. |
| Korolkovas, A., ?Essentials of Medicinal Chemistry?, Wiley-Interscience, 1988. |
| Kleemann, A., Engel, J., Kutscher,B., Reichert, D., Pharmaceutical Substances, Synthese, Patents, Applications, 4th edition, Thieme, 2001. |
| Program Requirements | Contribution Level | DK1 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 22 | 22 |
| Homework 1 | 1 | 2 | 2 |
| Quiz 1 | 1 | 1 | 1 |
| Final | 1 | 23.5 | 23.5 |
| Classroom Activities | 14 | 2 | 28 |
| Total Workload | 76.5 | ||
| ECTS Credit of the Course | 3.0 | ||
