| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Pharmaceutical Chemistry IV | ECZ402 | 8. Semester | 3 + 0 | 3.0 | 3.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | face to face |
| Course Coordinator |
Assist. Prof. Dr. Bahadır BÜLBÜL |
| Instructors | |
| Assistants | |
| Goals | The purpose of this course is to give a basic concept on general features, synthesis, mode of action, structure-activity relationship and biotransformation of the gastrointestinal system drugs, antiallergics, vitamins, diagnostic drugs and hormones. |
| Course Content | |
| Learning Outcomes |
- The student who completes this course learn 1. the general structures 2. Synthesis, 3. Mode of action, 4. Structure-activity relationship 5. Biotransformation and 6. Uses of gastrointestinal system drugs, antiallergics, diagnostic drugs, hormones and vitamines. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Digestants,carminatives, antiemetics | |
| 2. Week | Antiulcerative drugs, laxative and purgatives | |
| 3. Week | Antidiarrheal drugs, antiallergics | |
| 4. Week | Antiallergics, vitamins | |
| 5. Week | Diagnostics | |
| 6. Week | Introduction to hormones | |
| 7. Week | Peptide hormones | |
| 8. Week | Oral antidiabetics | |
| 9. Week | Introduction to steroid hormones, | |
| 10. Week | Estrogens and derivatives | |
| 11. Week | Progestogens, androgens and anabolic steroids | |
| 12. Week | Androgens and anabolic steroids | |
| 13. Week | Corticosteroids | |
| 14. Week | Autocoids |
| Akgün, H., Balkan, A., Bilgin, A.A., Çalış, Ü., Dalkara, S., Erdoğan, H., Erol Demir, D., Ertan, M.,Gökhan, N., Özkanlı, F., Palaska, E., Saraç, S. ve Şafak, C.,Tozkoparan.B.: Farmasötik Kimya, Ankara, 2004. |
| Foye, W.O.(ed): Principles of Medicinal Chemistry, 3rd ed, Lea & Febrigen, Philadelphia, 1989. |
| Delgado, J.N., Remers, W.A. (ed), Wilson & Gisvold?s Textbook of Organic Medicinal and Pharmaceutical Chemistry, 9th ed., Lippincott, Philadelphia, 1991. |
| Patrick, G.L., An Introduction to Medicinal Chemistry, Oxford University Press, Oxford, 1999. |
| Wolff, M.E., ?Burger?s Medicinal Chemistry and Drug Discovery?, Volume I-V, 4th edition, Wiley-Interscience, 1980-97. |
| Korolkovas, A., ?Essentials of Medicinal Chemistry?, Wiley-Interscience, 1988. |
| Program Requirements | Contribution Level | DK1 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 22 | 22 |
| Homework 1 | 1 | 2 | 2 |
| Quiz 1 | 1 | 1 | 1 |
| Final | 1 | 23.5 | 23.5 |
| Classroom Activities | 14 | 2 | 28 |
| Total Workload | 76.5 | ||
| ECTS Credit of the Course | 3.0 | ||
