| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Pharmaceutical Chemistry I Laboratory | ECZ393 | 5. Semester | 0 + 4 | 2.0 | 3.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | face to face |
| Course Coordinator |
Assist. Prof. Dr. Bahadır BÜLBÜL |
| Instructors |
Bahadır BÜLBÜL |
| Assistants | |
| Goals | The purpose of this course is to give information about laboratory safety rules, filtration, crystallisation, extraction, distillation and other laboratory technics and the synthesis and purifications of some drugs in laboratory conditions. |
| Course Content | |
| Learning Outcomes |
- Laboratory safety rules - Filtration, crystallisation, extraction, distillation and other laboratory technics - Synthesis and purifications of some drugs in laboratory conditions. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Demonstration (Lab. Safety) | |
| 2. Week | Demonstration (Lab. Technics) | |
| 3. Week | Demonstration (Organic Reactions) | |
| 4. Week | Synthesis of Isoamylnitrite | |
| 5. Week | Synthesis of Benzylic acid and Mercury oxide | |
| 6. Week | Synthesis of Benzyl and Dermatol | |
| 7. Week | Synthesis of Acetophenone and Benzoine | |
| 8. Week | Synthesis of m-Dinitrobenzene and Iodoform | |
| 9. Week | Synthesis of Benzoic acid and benzyl alcohol | |
| 10. Week | Synthesis of Diazodiaminobenzene | |
| 11. Week | Synthesis of Acetanilide and Barium sulfate | |
| 12. Week | Synthesis of Paracetamol | |
| 13. Week | Problem Solving and discussion | |
| 14. Week | Problem Solving and discussion |
| Akgün, H., Balkan, A., Bilgin, A.A., Çalış, Ü., Dalkara, S., Erdoğan, H., Erol Demir, D., Ertan, M.,Gökhan, N., Özkanlı, F., Palaska, E., Saraç, S. ve Şafak, C.,Tozkoparan.B.: Farmasötik Kimya, Ankara, 2004. |
| Foye, W.O.(ed): Principles of Medicinal Chemistry, 3rd ed, Lea & Febrigen, Philadelphia, 1989. |
| Delgado, J.N., Remers, W.A. (ed), Wilson & Gisvold?s Textbook of Organic Medicinal and Pharmaceutical Chemistry, 9th ed., Lippincott, Philadelphia, 1991 |
| Nicolaou KC. ?Classics in Total Synthesis? NewYork 1996 |
| Modern Organic Synthesis in the Laboratory, Oxford University Press, Inc.,2007 |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 1 | 1 |
| Homework 1 | 10 | 1 | 10 |
| Final | 1 | 2 | 2 |
| Practice | 1 | 10 | 10 |
| Classroom Activities | 14 | 2 | 28 |
| Total Workload | 51 | ||
| ECTS Credit of the Course | 3.0 | ||
