| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Pharmaceutical Microbiology | ECZ207 | 3. Semester | 3 + 0 | 3.0 | 3.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | Face to Face Education |
| Course Coordinator |
Assoc. Prof. Dr. Demet ERDÖNMEZ |
| Instructors |
Demet ERDÖNMEZ |
| Assistants | |
| Goals | The main purpose of this course isDevelopment of microbiology, living world and place of microorganisms, bacterial cell structure, classification of microorganisms. Characteristics and classification of bacteria, chlamydia, rickettsia, fungi, parasites and viruses. Biological features, genetics of microorganisms. Infections involving the nervous system, upper and lower respiratory tract, gastrointestinal and genitourinary system, skin and soft tissue, bones and joints, hospital infections, Antimicrobial agents, disinfectants, preservatives, antiseptics, antibiotics and mechanisms of action The formation of resistance to antibiotics, the basics of immunology, vaccines and immunization, the relationship between antibiotics, microorganisms, drugs and immune system, infections in immunocompromised individuals. Industrial microbiology, microbial contamination in the pharmaceutical industry, sterile pharmaceutical products Hospital hygiene, sanitation, disinfection and good production techniques in the pharmaceutical industry, To transfer knowledge about biotechnology and its application areas. |
| Course Content | |
| Learning Outcomes |
- Learns the Microbiology, classification of microorganisms, structure. - Defines the application areas of microbiology. - Establishes a relationship between microorganisms and the environment we live in. - Defines the requirements of microbiological quality applied in the pharmaceutical industry - Express the diseases caused by microorganisms, apply the methods used in prevention and control. - Applies Microbiological methods applied in the pharmaceutical industry. - Becomes competent in this important application area of microbiology and works in the pharmaceutical industry. - Explains how microorganisms cause contamination in pharmaceutical and cosmetic products. - Applies sterilization, disinfection and antisepsis methods required to protect pharmaceutical products from microorganisms. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Introduction to microbiology, classification and structure of microorganisms, Application areas of microbiology. | |
| 2. Week | Fine structure of bacteria, Reproduction, metabolism and enzymes of microorganisms, | |
| 3. Week | Changes seen in microorganisms, transfer of genetic material between bacteria. | |
| 4. Week | Sterilization, sterilization methods and controls, disinfection and antisepsis. | |
| 5. Week | Chemotherapeutic agents, mechanisms of action and resistance to microorganisms | |
| 6. Week | Enterobacteriacea vibrionacea, non-fermentative Gram (-) bacilli. | |
| 7. Week | Gram (+) cocci, Gram (-) cocci, Gram (+) spore-free bacilli, Gram (+) non-spore bacteria, Spirochaetaceae | |
| 8. Week | Diseases caused by bacteria of Mycoplasmataceae, Rickettsiaceae, Chlamydiaceae family. | |
| 9. Week | Diagnosis, treatment and prevention methods of diseases caused by nematodes, cestodes, trematodes, amoebas and parasites. | |
| 10. Week | Leishmania, diseases caused by plasmodium parasites, structure of fungal cell and some fungal infections | |
| 11. Week | Structure, classification and production of viruses, Hepatitis viruses, their structure, infections, prevention and control, HIV and rabies virus | |
| 12. Week | Sterility control of pharmaceutical products, microbial spoilage and preservation of pharmaceutical products. | |
| 13. Week | Ensuring microbiological control in areas where pharmaceutical products are produced. | |
| 14. Week | General Expression And Assessment |
| Hugo and Russell’s Pharmaceutical Microbiology. 7th edition. 2004 Blackwell Science Ltd. UK |
| Temel ve Klinik Mikrobiyoloji In: Ustaçelebi Ş, Ed., Ankara: Güneş Kitabevi, 1999 |
| Lecture notes (slides), lecture videos |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | DK7 | DK8 | DK9 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 6 | 6 |
| Homework 1 | 1 | 10 | 10 |
| Homework 2 | 1 | 10 | 10 |
| Final | 1 | 8.5 | 8.5 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 76.5 | ||
| ECTS Credit of the Course | 3.0 | ||
