| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Medical Biology and Genetics | ECZ113 | 1. Semester | 2 + 0 | 2.0 | 3.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Undergraduate |
| Course Type | |
| Mode of delivery | Lecture, question and answer, discussion |
| Course Coordinator |
Assist. Prof. Dr. Didem ORAL |
| Instructors |
Didem ORAL |
| Assistants | |
| Goals | This course aims to teach the molecules found in living organisms and the hereditary variations of these molecules |
| Course Content | Introduction to Cell Biology Cell Structure, Cell Membrane and Organelles Cell Cycle, Mitosis and Meiosis Cell Signal Transduction Mechanisms Cell Death Mechanisms DNA, RNA, Gene, Chromatin, Chromosome Mechanisms of Replication, Transcription and Translation Gene Expression and Epigenetic Mechanisms Mutation, Polymorphism Concepts and DNA Repair Mechanisms Cancer and its Mechanism Mendelian Genetics Molecular Genetic Diseases and Diagnostic Methods Cytogenetics |
| Learning Outcomes |
- 1. Define the concepts related to cell types, organelles and genetic material. 2. Explain the organelles of the cell, give information about the cytoskeleton 3. Explains the concepts of DNA, RNA, gene and chromosome 4. Describe DNA and RNA synthesis and explain DNA repair and regulation 5. Describes protein synthesis 6. will be able to explain cell cycle, mitosis and meiosis 7. Describe cell cycle stages and control points. 8. Explain the differences between mitosis and meiosis and genetic anomalies 9. Explain the differences between mitosis and meiosis and genetic anomalies 10. Provides information about the human genome project 11. Explain gene expression and epigenetic mechanisms 12. Explains the concepts of mutation, polymorphism, gives examples 13. Discusses DNA Repair Mechanisms 14. Defines Mendelian Genetics and Cytogenetic methods 15. Explains Molecular Genetic Diseases and Diagnostic Methods |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Hücre Biyolojisi Giriş | |
| 2. Week | Cell Structure, Cell Membrane and Organelles | |
| 3. Week | Cell Cycle, Mitosis and Meiosis | |
| 4. Week | Cell Signal Transduction Mechanisms | |
| 5. Week | Cell Death Mechanisms | |
| 6. Week | DNA, RNA, Gene, Chromatin, Chromosome | |
| 7. Week | Mechanisms of Replication, Transcription and Translation | |
| 8. Week | Epigenetic | |
| 9. Week | Gene Expression and Epigenetic Mechanisms | |
| 10. Week | Mutation, Polymorphism Concepts and DNA Repair Mechanisms | |
| 11. Week | Cancer and its mechanisms | |
| 12. Week | Mendelian Genetics | |
| 13. Week | Molecular Genetic Diseases and Diagnostic Methods | |
| 14. Week | cytogenetic |
| Molecular Biology of the Cell (Bruce Alberts et al.), The Cell A Molecular Approach (Geoffrey M. Cooper&Robert E. Hausman), Medical Genetics Thompson&Thompson (Robert L. Nussbaum et al.), Genetics (William S. Klug et al.), Lehninger Principles of Biochemistry (David L. Nelson&Michael M. Cox |
| Program Requirements | Contribution Level | DK1 | Measurement Method |
|---|
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Midterm 1 | 1 | 1.5 | 1.5 |
| Homework 1 | 13 | 1 | 13 |
| Homework 2 | 13 | 1 | 13 |
| Quiz 1 | 10 | 1 | 10 |
| Quiz 2 | 9 | 1 | 9 |
| Final | 1 | 2 | 2 |
| Classroom Activities | 14 | 2 | 28 |
| Total Workload | 76.5 | ||
| ECTS Credit of the Course | 3.0 | ||
