| Course Title | Code | Semester | L+U Hour | Credits | ECTS |
|---|---|---|---|---|---|
| Determination Of Sample Sizes | BIS502 | 3 + 0 | 3.0 | 8.0 |
| Prerequisites | None |
| Language of Instruction | Turkish |
| Course Level | Graduate |
| Course Type | |
| Mode of delivery | Face to Face |
| Course Coordinator |
Prof. Dr. Şengül CANGÜR |
| Instructor(s) | |
| Assistants | |
| Goals | It shows how to calculate the appropriate sample size to ensure that the scientific research results are more reliable and more economical. |
| Course Content | Rules and analytical approaches to be taken in deciding the appropriate sample size, which is one of the most important stages of research, will be addressed. For this purpose, we will focus on what should be taken into consideration when determining the appropriate sample size in the most frequently performed research types in practice, and the introduction and application of formulas that can be used in calculating the sample size. The statistical package program or web-based account pages that can be used to calculate sample size will also be examined. |
| Learning Outcomes |
- Describe the appropriate sample size concept and explain importance of it for research. - Know what needs to be taken into account when determining the sample size in the planning stage of researches. - Calculate the appropriate sample size for prevalence or field surveys conducted frequently in health field. - Know the steps to be followed when determining the appropriate sample size in experimental and clinical researches and can calculate it within ethical rules. - Know the advanced methods used to determine sample size and know the usage requirements of these methods. - Can calculate the appropriate sample size at various stages for market and drug researches. - Knowing what needs to be taken into account when calculating the sample size for investigating inter-variable relations and calculating the appropriate sample size. |
| Week | Topics | Learning Methods |
|---|---|---|
| 1. Week | Basic Principles and Frequently used Concepts in Sample Size Calculation | Course Hours |
| 2. Week | Concept of Hypothesis and Errors made in Hypothesis Testing | Course Hours Research Other Activities Preparation, After Class Study |
| 3. Week | Sample Size for One Sample Problems | Research Other Activities Course Hours Preparation, After Class Study |
| 4. Week | Sample Size for One Sample Problems | Course Hours Preparation, After Class Study Research Other Activities |
| 5. Week | Sample Size for Comparing Two Proportions | Course Hours Other Activities Preparation, After Class Study |
| 6. Week | Sample Size for Comparing More Than Two Means | Preparation, After Class Study Course Hours Research Other Activities |
| 7. Week | Sample Size for Analysis of Crosstabss | Course Hours Research Other Activities Preparation, After Class Study |
| 8. Week | Sample Size for Correlation and Simple Linear Regression Analyses | Course Hours Preparation, After Class Study Other Activities Research |
| 9. Week | Sample Size for Superiority, Equivalance and Non-inferiority Trials | Research Other Activities Course Hours Preparation, After Class Study |
| 10. Week | Sample Size for Logistic Regression Analysis | Preparation, After Class Study Course Hours Other Activities |
| 11. Week | Sample Size for Analysis of Survival Data | Course Hours Research Other Activities Preparation, After Class Study |
| 12. Week | Sample Size for Sequential Methods | Course Hours Preparation, After Class Study Other Activities |
| 13. Week | Sample Size for Drug Trials | Course Hours Preparation, After Class Study Other Activities |
| 14. Week | Sample Size for Animal Studies | Course Hours Preparation, After Class Study Other Activities |
| Prepared lecture notes (ppt presentation) |
| Zar, JH. 2009. Biostatistical Analysis. p:960, Prentice Hall 5 ed, USA, 2009. |
| Chow, S.C., Shao J., Wang, H. Sample Size Calculations in Clinical Research. Chapman & Hall/CRC Biostatistics Series, USA, 2004. |
| Program Requirements | Contribution Level | DK1 | DK2 | DK3 | DK4 | DK5 | DK6 | DK7 | Measurement Method |
|---|---|---|---|---|---|---|---|---|---|
| PY1 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 40,60 |
| PY2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 40,60 |
| PY3 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 40,60 |
| PY4 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 40,60 |
| PY5 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 40,60 |
| PY6 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 3 | 40,60 |
| PY7 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 40,60 |
| PY8 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 40,60 |
| PY9 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 40,60 |
| PY10 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 40,60 |
| PY11 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 40,60 |
| PY12 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 40,60 |
| 0 | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Course's Level of contribution | None | Very Low | Low | Fair | High | Very High |
| Method of assessment/evaluation | Written exam | Oral Exams | Assignment/Project | Laboratory work | Presentation/Seminar |
| Event | Quantity | Duration (Hour) | Total Workload (Hour) |
|---|---|---|---|
| Course Hours | 14 | 3 | 42 |
| Preparation, After Class Study | 13 | 4.5 | 58.5 |
| Research | 9 | 3 | 27 |
| Other Activities | 13 | 0.5 | 6.5 |
| Homework 1 | 13 | 2 | 26 |
| Final | 1 | 2 | 2 |
| Classroom Activities | 14 | 3 | 42 |
| Total Workload | 204 | ||
| ECTS Credit of the Course | 8.0 | ||
